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Health Sciences
Novartis-Penn Center for Advanced Cellular Therapeutics Unveiled at Penn Medicine
Physicians, scientists and leaders from the University of Pennsylvania’s Perelman School of Medicine and the global pharmaceutical company Novartis will gather Tuesday evening to unveil the Novartis-Penn Center for Advanced Cellular Therapeutics (CACT).
To Encourage Physical Activity, Potential to Lose a Financial Reward is More Effective than Gaining One, Penn Study Shows
Financial incentives aimed at increasing physical activity were most effective when the rewards were put at risk of being lost, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Penn Study: Visualizing a Parasite Crossing the Blood Brain Barrier
An estimated 30 percent of the world’s population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS.
Penn Engineers Use Network Science to Predict How Ligaments Fail
When doctors diagnose a torn ligament, it’s usually because they can see ruptures in the ligament’s collagen fibers, visible on a variety of different scans. However, they also often treat patients with many of the symptoms of a tear, but whose ligaments don’t show this kind of damage.
Improving Radiology’s Utility and Safety at Penn Dental Medicine
The oral cavity is a complex landscape, cavernous and full of irregular structures. Using a two-dimensional X-ray to map its variations can only reveal so much. That’s why a technological revolution that has made three-dimensional imaging of the teeth and jaws easier and safer has ushered in a transformation of practice in the dental clinic.
Two Penn Professors Call Attention to the Use of Race in Human Genetic Research
Two University of Pennsylvania professors are coauthors, along with two other scholars, on a perspective piece published this week in the journal Science that calls for an end to the use of genetic concepts of race in biological research.
Penn Study Prompts Reevaluation of Assumptions on Role of Internal Clock in Human Disease
Abolishing the 24-hour clock by knocking out a key gene during development accelerates aging and shortens lifespan by two thirds in mice, but this effect is absent if the gene deletion is delayed until after birth, according to a new study published this week in Science Translational Medicine by scientists from the Perelman School of Medicine at the University of Pennsylvania.
Penn Study Identifies Enzyme Key to Link Between Age-Related Inflammation and Cancer
For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Inhibitors of the enzyme are being developed as a new anti-cancer target.
"Gene Fusion" Mutation Uses Three-Way Mechanism To Drive Childhood Brain Cancers
A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP).
Penn Researchers Offer New Approach to Treating Cocaine Addiction
In the ongoing fight against drug addiction, researchers from the University of Pennsylvania’s School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug curr
In the News
6ABC.com
Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley
Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.
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Self
The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health
Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.
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NPR
Tuberculosis rates plunge when families living in poverty get a monthly cash payout
Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.
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Newsweek
Cancer breakthrough as ‘speckles’ may reveal best treatment
A paper co-authored by PIK Professor Shelley Berger finds that patterns of “speckles” in the heart of tumor cells could help predict how patients with a common form of kidney cancer will respond to treatment options.
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Time
Scientists are racing to develop a new bird flu vaccine
Drew Weissman and Scott Hensley of the Perelman School of Medicine are testing a vaccine to prevent a strain of H5N1 bird flu in chickens and cattle.
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