Health Sciences

Viral Gene Editing System Corrects Genetic Liver Disease in Newborn Mice

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected. Delivery of the vector to newborn mice improved their survival while treatment of adult animals, unexpectedly, made them worse, according to a new study by investigators from the Perelman School of Medicine at the University of Pennsylvania The team published their findings this week in Nature Biotechnology.

Karen Kreeger



In the News


6ABC.com

Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley

Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.

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Self

The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health

Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.

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NPR

Tuberculosis rates plunge when families living in poverty get a monthly cash payout

Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.

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Newsweek

Cancer breakthrough as ‘speckles’ may reveal best treatment

A paper co-authored by PIK Professor Shelley Berger finds that patterns of “speckles” in the heart of tumor cells could help predict how patients with a common form of kidney cancer will respond to treatment options.

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Time

Scientists are racing to develop a new bird flu vaccine

Drew Weissman and Scott Hensley of the Perelman School of Medicine are testing a vaccine to prevent a strain of H5N1 bird flu in chickens and cattle.

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