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Health Sciences
Off-Kilter: Penn Study Identifies Differences in Treatment Effect on Out-of-Balance Microbiome in Crohn's Disease
Different treatments for Crohn's disease in children affects their gut microbes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania
NIH New Innovator Award Goes to Penn Bioengineer for Study of ‘3-D Epigenome’
The National Institutes of Health have named Jennifer Phillips-Cremins, an assistant professor in the University of Pennsylvania School of Engineering and Applied Science’s Department of Bioengineering, as a member of its
Turncoat Protein Regulates Sensitivity of Breast Cancer Cells to Drug, Providing New Target for Preventing Relapses, Finds Penn Study
A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a common cancer drug, found researchers at the Perelman School of Medicine at the University of Pennsylvania
Penn Medicine Researchers Discover Hidden Brain Pathways Crucial to Communication
Being able to understand speech is essential to our evolution as humans. Hearing lets us perceive the same word even when spoken at different speeds or pitches, and also gives us extra sensitivity to unexpected sounds.
Penn Team Maps First Comprehensive Profile of Non-Protein-Coding RNAs to Provide Clinicians with New Way to Diagnose Array of Cancers
Growing insights about a significant, yet poorly understood, part of the genome – the “dark matter of DNA” -- have fundamentally changed the way scientists approach the study of diseases. The human genome contains about 20,000 protein-coding genes – less than 2 percent of the total – but 70 percent of the genome is made into non-coding RNA.
Mother’s Stress Alters Babies’ Gut and Brain
Stress during the first trimester of pregnancy alters the population of microbes living in a mother’s vagina. Those changes are passed on to newborns during birth and are associated with differences in their gut microbiome as well as their brain development, according to a study by Penn researchers.
Penn Study Stops Vision Loss in Late-stage Canine X-linked Retinitis Pigmentosa
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Penn and BU Study Says Obesity Doesn’t Protect Patients With Cardiovascular Disease
Demographers Samuel Preston of the University of Pennsylvania and Andrew Stokes of Boston University set out to solve a puzzle: Why is it that study after study shows obese or overweight people with cardiovascular disease outliving their normal
Penn Vet-Temple Team Characterizes Genetic Mutations Linked to a Form of Blindness
Achromatopsia is a rare, inherited vision disorder that affects the eye’s cone cells, resulting in problems with daytime vision, clarity and color perception. It often strikes people early in life, and currently there is no cure for the condition.
Penn, University of California and Army Research Lab Show How Brain’s Wiring Leads to Cognitive Control
How does the brain determine which direction to let its thoughts fly? Looking for the mechanisms behind cognitive control of thought, researchers at the University of Pennsylvania, University of California and United States Army Research Laboratory have used brain scans to shed new light on this question.
In the News
6ABC.com
Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley
Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.
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Self
The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health
Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.
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NPR
Tuberculosis rates plunge when families living in poverty get a monthly cash payout
Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.
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Newsweek
Cancer breakthrough as ‘speckles’ may reveal best treatment
A paper co-authored by PIK Professor Shelley Berger finds that patterns of “speckles” in the heart of tumor cells could help predict how patients with a common form of kidney cancer will respond to treatment options.
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Time
Scientists are racing to develop a new bird flu vaccine
Drew Weissman and Scott Hensley of the Perelman School of Medicine are testing a vaccine to prevent a strain of H5N1 bird flu in chickens and cattle.
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