An increasing number of studies show that chronically restricted sleep to less than seven hours per day impairs performance, increases the risk for errors and accidents, and is associated with negative health consequences like obesity, diabetes, and cardiovascular disease.

Greg Richter ・December 12, 2014

Frequent kidney dialysis is essential for the approximately 350,000 end-stage renal disease (ESRD) patients in the United States. But it can also cause systemic inflammation, leading to complications such as cardiovascular disease and anemia, and patients who rely on the therapy have a five-year survival rate of only 35 percent.

Karen Kreeger ・December 11, 2014

Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicineresearchers Ezekiel J. Emanuel, MD, PhD, and Justin E. Bekelman, MD.

Steve Graff ・December 10, 2014

Researchers at Penn Medicine, in collaboration with a multi-center international team, have shown that a protease inhibitor, simeprevir, a once a day pill, along with interferon and ribavirin has proven as effective in treating chronic Hepatitis C virus infection (HCV) as telaprevir with interferon and ribavirin, the standard of care in developing countries.

Lee-Ann Donegan ・December 10, 2014

By Madeleine Stone  @themadstone

Katherine Unger Baillie ・December 8, 2014

A new chemical-genetic therapy restores light responses to the retinas of blind mice and dogs and enables the mice to guide their behavior according to visual cues, setting the stage for clinical trial in humans.

Katherine Unger Baillie ・December 8, 2014

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease’s progress towards kidney failure.

Karen Kreeger ・December 1, 2014