4/22
Health Sciences
Penn Medicine: Personalized Gene Therapy Locks Out HIV, Paving the Way to Control Virus Without Antiretroviral Drugs
University of Pennsylvania researchers have successfully genetically engineered the immune cells of 12 HIV positive patients to resist infection, and decreased the viral loads of some patients taken off antiretroviral drug therapy (ADT) entirely—including one patient whose levels became undetectable.
Anatomical Discovery by Penn Team Gives Insight into Blinding Retinal Diseases
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Penn Researchers Model a Key Breaking Point Involved in Traumatic Brain Injury
Even the mildest form of a traumatic brain injury, better known as a concussion, can deal permanent, irreparable damage. Now, an interdisciplinary team of researchers at the University of Pennsylvania is using mathematical modeling to better understand the mechanisms at play in this kind of injury, with an eye toward protecting the brain from its long-term consequences.
Penn Study Results Confirm BMI is a Direct Cause of Type 2 Diabetes and High Blood Pressure
Using new genetic evidence, an international team of scientists led by experts at the Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia has found that an increased body mass index (BMI) raised the risk for both type 2 diabetes and higher blood pressure.
Muscle-controlling Neurons Know When They Mess Up, According to Penn Research
Whether it is playing a piano sonata or acing a tennis serve, the brain needs to orchestrate precise, coordinated control over the body’s many muscles. Moreover, there needs to be some kind of feedback from the senses should any of those movements go wrong.
Antonia Villarruel Named Dean of Penn School of Nursing
Antonia Villarruel has been named dean of the School of Nursing at the University of Pennsylvania, effective July 1. The announcement was made today by Penn President Amy Gutmann and Provost Vincent Price.
Penn Medicine Researchers Ask: Can A Story Help Doctors Curb the Prescription Opioid Abuse Epidemic?
In the fight against a nationwide prescription opioid abuse epidemic, Penn Medicine researchers are using storytelling to help doctors recall important, potentially lifesaving national guidelines on how to prescribe these medications.
Penn Study Shows Way to Make Treatment of Rare Blood Disorder More Affordable and Effective
A University of Pennsylvania research team has defined a possible new way to fight a disease that is currently treatable only with the most expensive drug available for sale in the United States.
Penn Researchers Show Nuclear Stiffness Keeps Stem Cells and Cancer Cells in Place
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus’ DNA compared to a stiffer nucleus.
Penn Study: Blocking Autophagy with Malaria Drug May Help Overcome Resistance to BRAF Drugs in Melanoma
Half of melanoma patients with the BRAF mutation have a positive response to treatment with BRAF inhibitors, but nearly all of those patients develop resistance to the drugs and experience disease progression.
In the News
UPenn hosts free online panel for LGBTQ+ workplace inclusion
The Eidos LGBTQ+ Health Initiative, led by José Bauermeister and Jessica Halem of the School of Nursing, will host a free online panel in April on the integration of LGBTQ+ people in the workforce.
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How to die in good health
PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
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Mayor Parker’s plan to ‘remove the presence of drug users’ from Kensington raises new questions
Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
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Homeward bound: When a Penn Medicine nurse was diagnosed with uterine cancer, she turned to the service dogs she helped to train
A profile highlights Maria Wright of Penn Medicine Lancaster General Health, from her volunteer work connecting people with service dogs to her cancer diagnosis and her own journey applying for a service dog.
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How many patients would recommend their Philly-area hospital to family and friends? Check your local hospital
The Hospital of the University of Pennsylvania has been named one of the most recommended acute-care facilities by patients in the Philadelphia area.
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