PHILADELPHIA – Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease.

Jessica Mikulski ・December 26, 2012

PHILADELPHIA — One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it.  Researchers from the Perelman School of Medicine at the University of Pennsylvania, working with collaborators from Drexel University, The Children's Hospital of Philadelphia, and Johns Hop

Karen Kreeger ・December 26, 2012

PHILADELPHIA — Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, AIDS, Alzheimer's disease, multiple sclerosis, and  cancer.  As such, finding and exploiting calpain inhibitors is an important area of research. 

Karen Kreeger ・December 26, 2012

PHILADELPHIA — When trying to determine the root cause of a person's dementia, using an MRI can effectively and non-invasively screen patients for Alzheimer's disease or Frontotemporal Lobar Degeneration (FTLD), according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

Kim Menard ・December 26, 2012

PHILADELPHIA — The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death.

Karen Kreeger ・December 19, 2012

PHILADELPHIA — New research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, suggesting that cocaine-induced changes in physiology are passed down from father to son.

Jessica Mikulski ・December 17, 2012

PHILADELPHIA — In the waning days of 2012, two words have dominated the post-election discourse: “fiscal cliff.” The cliff is a combination of impending budgetary measures that will take effect in January if a legislative compromise is not reached.

Evan Lerner ・December 13, 2012

PHILADELPHIA — L. Scott Levin, MD, FACS, was recently elected to the American College of Surgeons’ (ACS) Board of Regents.

Katie Delach ・December 12, 2012

PHILADELPHIA — Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

Katherine Unger Baillie ・December 7, 2012