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Health Sciences
Penn Study Shows Hospital Nurses Dissatisfied With Health Benefits
Researchers at the University of Pennsylvania have found that nearly 41 per cent of nurses working in American hospitals and health-care settings were dissatisfied with their health-care benefits. The figure is more than double that of nurses working in other settings and indicates broad-based disincentives for attracting nurses to work at the bedside.
Immune Cells Protect Body from Invaders, According to Penn Researchers
PHILADELPHIA - So-called barrier sites -- the skin, gut, lung – limit the inner body’s exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body’s barriers.
Sideline Test Accurately Detects Athletes’ Concussions in Minutes, Penn Study Shows
PHILADELPHIA – A simple test performed at the sideline of sporting events can accurately detect concussions in athletes, according to study by researchers at the University of Pennsylvania School of Medicine. Current sideline tests can leave a wide amount a brain function untested following concussion.
New Study from Penn Medicine: Antidepressant Use Reduced Hot Flashes in Menopausal Women
“Our findings suggest that among healthy women who were not depressed or anxious, a 10 to 20 milligram dose of escitalopram – which is well below the dosage level for psychiatric use – provides a nonhormonal, off-label option that is effective and well-tolerated in the management of menopausal hot flashes,” said Elle
Researchers Uncover New Gene for Heart Failure in Caucasians
Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge.
Certain Genetic Profiles Increase Risk of Coronary Artery Disease, While Others Increase Risk of Heart Attack
(PHILADELPHIA) – Coronary artery disease (CAD) is the single largest cause of death in adults in the United States. Until recently, the genetic basis of CAD has been largely unknown, with just a few proven genes (typically genes for cholesterol disorders) accounting for very little of the disease in the population.
Penn Study Shows New Measure Trumps HDL Levels in Protecting Against Heart Disease
(PHILADELPHIA) – The discovery that high levels of high-density lipoprotein (HDL) cholesterol (the “good cholesterol”) is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain.
Male Pattern Balding May Be Due to Stem Cell Inactivation, According to Penn Study
PHILADELPHIA – Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level.
Malfunctioning Gene Associated With Lou Gehrig’s Disease Leads to Nerve-Cell Death in Mice
PHILADELPHIA – Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), and frontotemporal lobar degeneration (FTLD) are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps.
Structure of Key Molecule in Immune System Provides Clues for Designing Drugs, According to Penn Study
PHILADELPHIA - A team from the University of Pennsylvania School of Medicine and Utrecht University has deciphered a key step in an evolutionarily old branch of the immune response. This system, called complement, comprises a network of proteins that “complement” the work of antibodies in destroying foreign invaders.
In the News
Sugar-coated gold nanoparticles could replace some antibiotics
According to a Penn Medicine study, a new therapy involving laser light and sugar-coated gold nanoparticles can reduce tooth decay and infected wounds without needing antibiotics.
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A new strategy to attack aggressive brain cancer shrank tumors in two early tests
A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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Alzheimer’s may be caused by a build-up of fat in brain cells
A study by Michael Haney of the Perelman School of Medicine suggests that the root cause of Alzheimer’s is a build-up of fat droplets in brain cells.
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Cats aren’t jerks. They’re just misunderstood
James Serpell of the School of Veterinary Medicine says that the domestic cat suffers from its legacy of being a not-quite-wild animal on the margins of society.
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Philadelphia hospital program adds psychologists to bridge mental health services for trauma survivors
A new psychology team at the Penn Trauma Violence Recovery Program has provided about 46 survivors with short- and long- term therapy, featuring remarks from Elinore Kaufman and Lily Brown of the Perelman School of Medicine.
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