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First Microscopic Video of Blood Clot Contraction Reveals How Platelets Naturally Form Unobtrusive Clots

First Microscopic Video of Blood Clot Contraction Reveals How Platelets Naturally Form Unobtrusive Clots

The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers from the Perelman School of Medicine at the University of Pennsylvania a new look at a natural process that is part of blood clotting. A team led by John W.

Karen Kreeger

Paving a New Path to Parenthood: Penn Medicine Launches First Clinical Trial for Uterine Transplant in the Northeast

Paving a New Path to Parenthood: Penn Medicine Launches First Clinical Trial for Uterine Transplant in the Northeast

Penn Medicine will conduct the Northeast’s first clinical trial of uterine transplants, to provide women with Uterine Factor Infertility (UFI) - an irreversible form of female infertility that affects as many as 5 percent of women worldwide and 50,000 women in the United States - with a new path to parenthood.

Abbey Anderson

Penn Biologists Show How Chromosomes ‘Cheat’ for the Chance to Get Into an Egg

Penn Biologists Show How Chromosomes ‘Cheat’ for the Chance to Get Into an Egg

Each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. Theoretically, when you create a gamete — a sperm or an egg —  each copy has a 50-50 shot at being passed on. But the reality isn’t so clearcut.

Katherine Unger Baillie

Penn’s Restoring Active Memory Project Adds Task and Patient Data to Publicly Available Human Brain Dataset

Penn’s Restoring Active Memory Project Adds Task and Patient Data to Publicly Available Human Brain Dataset

The Restoring Active Memory project run by the University of Pennsylvania has just released human intracranial brain recording and stimulation data for 102 new patients and a new spatial-navigation task developed by researchers at Columbia University.

Michele W. Berger

Connecting Homeless Populations With Health Care

Connecting Homeless Populations With Health Care

Homeless people are uniquely vulnerable, at risk of a variety of health problems, including chronic illness, hunger, pain, and infections. While resources exist to provide homeless populations with health insurance and care, those resources don’t always make their way to the people who need them.

Katherine Unger Baillie

Targeting enzyme in ‘normal’ cells may impede pancreatic cancer’s spread, Penn Vet team shows

Targeting enzyme in ‘normal’ cells may impede pancreatic cancer’s spread, Penn Vet team shows

Cancer of the pancreas is a deadly disease, with a median survival time of less than six months. Only one in 20 people with pancreatic cancer survives five years past the diagnosis. The reason is the cancer’s insidiousness; tumor cells hide deep inside the body, betraying no symptoms until late in the disease, when the cancer has almost invariably spread to other organs.

Katherine Unger Baillie

Penn Medicine: Blood Flow in the Developing Heart Guides Maturation of Heart Valves

Penn Medicine: Blood Flow in the Developing Heart Guides Maturation of Heart Valves

Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors – changes in gene expression versus an alteration in the genetic code -- play an important role.