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2004 Results
Penn/Vanderbilt Study: Genetic Risk Factors of Disparate Diseases Share Similar Biological Underpinnings

Penn/Vanderbilt Study: Genetic Risk Factors of Disparate Diseases Share Similar Biological Underpinnings

The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsylvania, the University of Arizona Health Sciences

Karen Kreeger

Penn Institute for Biomedical Informatics and colleagues Identify "Roadmap" of Disease Mechanisms to Identify Candidate Drug Targets

Penn Institute for Biomedical Informatics and colleagues Identify "Roadmap" of Disease Mechanisms to Identify Candidate Drug Targets

The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsyl

Karen Kreeger

Penn Study: A Long-noncoding RNA Regulates Repair of DNA Breaks in Triple-Negative Breast Cancer Cells

Penn Study: A Long-noncoding RNA Regulates Repair of DNA Breaks in Triple-Negative Breast Cancer Cells

The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes – less than 2 percent of the total – but 70 percent of the genome is made into non-gene-encoding RNA.

Karen Kreeger

Penn Team Restores Memory Formation Following Sleep Deprivation in Mice

Penn Team Restores Memory Formation Following Sleep Deprivation in Mice

Pulling an all-nighter may seem like a good way to cram before a test, yet science tells us memory suffers when sleep is sacrificed. A new study suggests that it doesn’t have to.

Katherine Unger Baillie

Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis

Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie

Katie Delach

Penn Study Suggests Changes in Skin "Microbiome" During Canine Atopic Dermatitis Could Lead to Antibiotic-Free Therapies for Human and Canine Disease

Penn Study Suggests Changes in Skin "Microbiome" During Canine Atopic Dermatitis Could Lead to Antibiotic-Free Therapies for Human and Canine Disease

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.

Katie Delach

Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis

Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie

Katie Delach

Penn Medicine Study Uncovers New Pathways that Control Skin Tanning and Lightening

Penn Medicine Study Uncovers New Pathways that Control Skin Tanning and Lightening

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

Katie Delach