Health Sciences

The Center for High Impact Philanthropy at the University of Pennsylvania has developed a free online guide for people who want to save lives by reducing illness and homelessness related to drug or alcohol use, and help more people access the care they need to get better more quickly.

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director of the Abramson Cancer Center, study body clock proteins associated with cancer cells.

A simple blood test can detect early markers of “reinvigorated” T cells and track immune responses in metastatic melanoma patients after initial treatment with the anti-PD-1 drug pembrolizumab, researchers from the Abramson Cancer Center of the University of Pennsylvania report in new research being presented at the inaugural CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.

Even patients with health insurance who have multiple myeloma may be vulnerable to “financial toxicity” – including those who make over $100,000 a year – because of the higher use of novel therapeutics and extended duration of myeloma treatment, researchers from Penn’s Abramson Cancer Center report in this week’s 

It’s not only physicians and nurses who can make a difference in health care. Sometimes it takes a history major and some careful observation to help effect positive change.

Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood.

People with congenital stationary night blindness, or CSNB, have normal vision during the day but find it difficult or impossible to distinguish objects in low light. This rare condition is present from birth and can seriously impact quality of life, especially in locations and conditions where artificial illumination is not available.

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers.

Like the hairs they resemble, cilia come in all lengths, from short to long.  But unlike the hair on our heads, the length of sensory cilia on nerve cells in our noses is of far more than merely cosmetic significance.

Consequences of incarceration on former inmates and their families are well known. But how does imprisonment affect the health care system as a whole?