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Scientists from Penn and CHOP Confirm Link Between Missing DNA and Birth Defects

Scientists from Penn and CHOP Confirm Link Between Missing DNA and Birth Defects

In 2010, scientists in Italy reported that a woman and her daughter showed a puzzling array of disabilities, including epilepsy and cleft palate. The mother had previously lost a 15-day-old son to respiratory failure, and the research team noted that the mother and daughter were missing a large chunk of DNA on their X chromosome.

Katherine Unger Baillie

Penn Researchers Model a Key Breaking Point Involved in Traumatic Brain Injury

Penn Researchers Model a Key Breaking Point Involved in Traumatic Brain Injury

Even the mildest form of a traumatic brain injury, better known as a concussion, can deal permanent, irreparable damage. Now, an interdisciplinary team of researchers at the University of Pennsylvania is using mathematical modeling to better understand the mechanisms at play in this kind of injury, with an eye toward protecting the brain from its long-term consequences.

Evan Lerner

Penn’s Morris Arboretum Is a Year-round Oasis

Penn’s Morris Arboretum Is a Year-round Oasis

It may be that many people don’t think of the Morris Arboretum when it is cold and snowy outside, but the University of Pennsylvania site offers unique scenic views and seasonal activities aplenty even in the winter. 

Jeanne Leong

Muscle-controlling Neurons Know When They Mess Up, According to Penn Research

Muscle-controlling Neurons Know When They Mess Up, According to Penn Research

Whether it is playing a piano sonata or acing a tennis serve, the brain needs to orchestrate precise, coordinated control over the body’s many muscles. Moreover, there needs to be some kind of feedback from the senses should any of those movements go wrong.

Evan Lerner

Penn Researchers Show Nuclear Stiffness Keeps Stem Cells and Cancer Cells in Place

Penn Researchers Show Nuclear Stiffness Keeps Stem Cells and Cancer Cells in Place

Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus’ DNA compared to a stiffer nucleus.

Evan Lerner

Three Penn Researchers Awarded Sloan Fellowships

Three Penn Researchers Awarded Sloan Fellowships

Three University of Pennsylvania faculty members are among this year’s Sloan Fellowship recipients. Since 1955, the Alfred P. Sloan Foundation has granted yearly fellowships to early-career scientists and scholars whose achievements and potential identify them the next generation of scientific leaders.

Evan Lerner

John Legend to Speak at Penn’s 258th Commencement

John Legend to Speak at Penn’s 258th Commencement

John Legend, a nine-time Grammy Award-winning soul artist, philanthropist and Penn alumnus will deliver the address at the University of Pennsylvania’s Commencement on Monday, May 19, Leslie Laird Kruhly, Vice President and University Secretary announced.

Jeanne Leong