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Penn Engineers Make First Full Network Model of the Musculoskeletal System

Penn Engineers Make First Full Network Model of the Musculoskeletal System

Network science examines how the actions of a system’s individual parts affect the behavior of the system as a whole. Some commonly studied networks include computer chip components and social media users, but University of Pennsylvania engineers are now applying network science to a much older system: the human body.

Evan Lerner

Improvements in mortality rates are slowed by rise in obesity in the United States

Improvements in mortality rates are slowed by rise in obesity in the United States

With countless medical advances and efforts to curb smoking, one might expect that life expectancy in the United States would improve. Yet according to recent studies, there’s been a reduction in the rate of improvement in American mortality during the past three decades.

Ali Sundermier

Penn-led Team Uncovers the Physiology Behind the Hour-long Mating Call of Midshipman Fish

Penn-led Team Uncovers the Physiology Behind the Hour-long Mating Call of Midshipman Fish

According to the Guinness World Records, the longest any person has held a continuous vocal note is just shy of two minutes. That’s quite an achievement.Compared to the Pacific midshipman fish, however, the endurance of the human vocal cord is no match. Midshipman fish can generate a mating call that emits continuously from their bodies for a full hour.

Katherine Unger Baillie

‘Silent Code’ of Nucleotides, Not Amino Acids, Determines Discrete Functions of Proteins Vital For Life

‘Silent Code’ of Nucleotides, Not Amino Acids, Determines Discrete Functions of Proteins Vital For Life

Humans possess six forms of the protein actin, which perform essential functions in the body. Two in particular, β-actin and γ-actin, are nearly identical, only differing by four amino acids. Yet these near-twin proteins carry out distinct roles. A long standing question for biologists has been, how is this possible?

Katherine Unger Baillie

Researcher awarded Swartz Fellowship to investigate mechanisms of learning and memory

Researcher awarded Swartz Fellowship to investigate mechanisms of learning and memory

Gaia Tavoni, a postdoctoral fellow of the Computational Neuroscience Initiative, has been named a Swartz Foundation Fellow for Theory in Neuroscience for her research proposal suggesting pathways to investigate the brain mechanisms involved in learning and memory.

Ali Sundermier

Penn Engineers: Bone Marrow Transplant Stem Cells Can 'Swim' Upstream

Penn Engineers: Bone Marrow Transplant Stem Cells Can 'Swim' Upstream

When a cancer patient receives a bone marrow transplant, time is of the essence. Healthy stem cells, which can restart the production of blood cells and immune system components after a patient’s own are compromised, need to make their way from the circulatory system into the bones as quickly as possible.

Evan Lerner , Ali Sundermier

Q&A with H. Carton Rogers

Q&A with H. Carton Rogers

Almost 43 years ago, H. Carton Rogers was hired as the director of public and technical services in what was then known as Penn’s Medical Library. His first task on the job? To literally move the Biology Library down Hamilton Walk from the Leidy Building to integrate it with the medical collection and create the Biomedical Library.

Commonalities in Late Stages of Different Inherited Blinding Diseases Suggest Targets for Therapy

Commonalities in Late Stages of Different Inherited Blinding Diseases Suggest Targets for Therapy

Gene therapy holds promise for treating a variety of diseases, including some inherited blinding conditions. But for a gene therapy to be effective, one must know the precise gene responsible for a given individual’s disorder and develop a tailored treatment.

Katherine Unger Baillie

Coalition Seeks to Increase Transparency on Life Sciences Career Prospects

Coalition Seeks to Increase Transparency on Life Sciences Career Prospects

Nine American research universities and a major cancer institute today announced plans to give would-be life scientists clear, standardized data on graduate school admissions, education and training opportunities and career prospects.

Katherine Unger Baillie , Dennis O'Shea