Perelman School of Medicine

CRISPR-edited lung cells (green) with EGFP fluorescent protein.

Researchers use gene editing with CRISPR to treat lethal lung diseases before birth

Using CRISPR gene editing, a team from Penn Medicine and Children’s Hospital of Philadelphia have thwarted a lethal lung disease, in which a harmful mutation causes death within hours after birth.

Anita Allen, Daniel Rader, and Zeid Ra'ad Al Hussein

Three from Penn elected to the American Academy of Arts and Sciences

Vice Provost for Faculty Anita Allen of the Law School and the School of Arts and Sciences, Daniel Rader of the Perelman School of Medicine, and Zeid Ra’ad Al Hussein of Perry World House join a group recognized for their world-class leadership and expertise.

Astronaut in a space suit on a spacewalk outside the International Space Station.

How a year in space affects the brain

Penn Medicine’s Mathias Basner discusses the NASA Twins Study, which analyzed astronaut Scott Kelly’s physical and mental health after he spent 340 days in space, and found that Kelly’s performance on a cognitive test battery dropped when he returned to Earth for six months.

Chips in Space

Microfluidic devices lined with human cells are headed to the International Space Station in early May, part of an effort to understand why astronauts get sick more easily in orbit.

person wearing a camouflage jacket in a wheelchair holding a tumbler of alcohol

Study reveals overlapping and distinct genes associated with heavy drinking and alcoholism

In the largest-ever genome-wide association study of both traits in the same population, a team of researchers found 18 genetic variants of significance associated with either heavy alcohol consumption, AUD, or both.

doctor with a gloved hand examines young child's arm during a skin test screening

Topical targeted therapies show promise in treatment of skin cancer

A Penn study finds fewer side effects with small-molecule kinase inhibitors compared to standard ointment when treating precancerous skin lesions.

A model of the internal brain hemisphere under a glass skull.

Researchers discover the source of new neurons in brain hippocampus

The findings extend the understanding of how a continuous supply of neurons throughout life is connected with learning and memory.

Microscopic images of cells are blue with diffuse splotches of pink on each cell.

Unlocking the female bias in lupus

The majority of lupus patients are female, and new findings from Montserrat Anguera of the School of Veterinary Medicine and colleagues shed light on why. The research suggests that female lupus patients don’t fully silence their second X chromosome in T cells, leading to an immune response gone awry.

A DIY colorectal cancer screening kit

At-home screening kits are found to be effective, with roughly a quarter of patients overdue for screenings mailing the completed kits back within two months.

view of Amy Gutmann on stage from the audience at the Power of Penn event with a large video screen behind her showing a video

The Power of Penn at the Met

One year into the Power of Penn campaign, President Amy Gutmann hosted a panel discussion with three professors to usher in another year of inclusion, innovation, and impact on a local and global scale.

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