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Penn Research Identifies Brain Network that Controls Spread of Seizures

Penn Research Identifies Brain Network that Controls Spread of Seizures

A flurry of coordinated activity in a brain-spanning network of neurons may sound like the formation of a brilliant new idea, but it is actually the description of a seizure. Understanding why and how this synchronization spreads would be a critical tool in treating severe epilepsy.

Evan Lerner

Penn Study: Lengthy ER Visits for Psychiatric Patients Often Result in Transfer, Not Treatment

Penn Study: Lengthy ER Visits for Psychiatric Patients Often Result in Transfer, Not Treatment

Cutbacks in capacity at state and county mental hospitals have forced more and more psychiatric patients to seek treatment . But a new study led by the Perelman School of Medicine at the University of Pennsylvania, found that people who visit emergency rooms for mental health care were transferred to another facility at six times the rate of people who visit ERs for non-psychiatric conditions, and could wait almost two hours longer.

Katie Delach

Penn Medicine: New Mouse Model Points to Drug Target Potentially Useful for Increasing Social Interaction in Autism

Penn Medicine: New Mouse Model Points to Drug Target Potentially Useful for Increasing Social Interaction in Autism

A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

Karen Kreeger

Penn: Blinding Disease in Canines and Humans Shares Causative Gene, Pathology

Penn: Blinding Disease in Canines and Humans Shares Causative Gene, Pathology

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions. One such disease is Senior Løken Syndrome, a rare condition that can involve both a severe kidney disease and the blinding disease Leber congenital amaurosis, or LCA.

Katherine Unger Baillie

Penn Team Identifies Strategy to Reverse the Disease Dyskeratosis Congenita

Penn Team Identifies Strategy to Reverse the Disease Dyskeratosis Congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. Typically diagnosed in childhood, the disorder causes stem cells to fail, leading to significant problems including bone marrow failure, lung fibrosis, dyskeratosis of the skin and intestinal atrophy and inflammation.

Katherine Unger Baillie

Penn Study: Codependence of Cell Nucleus Proteins Key to Understanding Fatty Liver Disease

Penn Study: Codependence of Cell Nucleus Proteins Key to Understanding Fatty Liver Disease

A new appreciation for the interplay between two cell nucleus proteins that lead both intertwined and separate lives is helping researchers better understand fatty liver disease, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

Karen Kreeger