Perelman School of Medicine

A neuroscientist from the Perelman School of Medicine at the University of Pennsylvania, with a colleague from the Johns Hopkins University School of Medicine, authored an essay calling for scientists to do what they can to reduce their carbon footprint while engaging in professional activiti

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, yet exactly how they form is somewhat of a mystery.

Imagine a room or a landscape or a city street.

Penn's Innovative Community Health Worker (CHW) model, shown to reduce admissions and lead to better health outcomes for hospitalized patients, can now be used in outpatient settings, according to a study from researchers at the Perelman School of Medicine in the journalPopulation Health Management.

Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes.

Understanding the origins of emerging diseases – as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite’s ability to cause infected red blood cells to bind to the inner lining of blood vessels.

At least half of Parkinson’s disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs (VA) Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients. The findings will be published in the March 21 issue of JAMA Neurology.

Possessing two X chromosomes is a double-edged sword, immunologically speaking. Females are better at fighting off infection than males, but they are also more susceptible to many autoimmune conditions, such as lupus.

Benjamin Aaron Garcia, PhD, a Presidential Professor of Biochemistry and Biophysics at the Perelman School of Medicine at the University of Pennsylvania, has been selected to receive the 2016Protein Science Young Investigator Award.

WHO:            Weingarten Learning Resources Center                      University of Pennsylvania