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Advances in cancer research
Microscopic rendering of interleukin 18 protein.

Interleukin-18 is a protein which in humans is encoded by the IL18 gene. “We designed an ‘armored’ CAR that secretes IL18 where we found it to have potent antitumor efficacy in our preclinical studies,” said Carl June. (Image: Penn Medicine News)

Advances in cancer research

Recent research shows promise in a novel CAR T therapy after cancer relapse, and a novel treatment for multiple myeloma.

From Penn Medicine News

A gateway from high school to Penn Medicine
Closeup of a stethoscope held up by a medical worker.

A gateway from high school to Penn Medicine

Penn Medicine’s Pathways Emerging Careers Program invites Philadelphia high school graduates to start a career with Penn Medicine with extra coaching, training, and mentoring.

Meredith Mann

At Engaging Minds, three Penn Integrates Knowledge Professors take the stage
Lance Freeman, at a podium on a stage, speaks to a crowd with a presentation displayed in the background

At Engaging Minds, three Penn Integrates Knowledge Professors take the stage

Alumni heard Lance Freeman examine racial equity in city planning, Dolores Albarracín talk about how conspiracy theories take hold, and Kevin Johnson discuss the importance of clear science communication.

Michele W. Berger

Study shows promise of new anti-KRAS drug for pancreatic cancer
Microscopic view of a DNA chain with a genetic mutation.

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer.

From Penn Medicine News

Two from Penn named Distinguished Members of the Association for Computing Machinery
Jane Li and Li Shen.

Jing (Jane) Li of the University of Pennsylvania’s School of Engineering and Applied Science, and Li Shen of Penn’s Perelman School of Medicine. (Images: Courtesy of the School of Engineering and Applied Science and the Perelman School of Medicine)

Two from Penn named Distinguished Members of the Association for Computing Machinery

Jing (Jane) Li of the School of Engineering and Applied Science and Li Shen of the Perelman School of Medicine have been named distinguished members of the Association for Computing Machinery.

Michele W. Berger, Michele W. Berger , Nathi Magubane

How ketamine acts as ‘switch’ in the brain
Microscopic view of two synapses.

How ketamine acts as ‘switch’ in the brain

Penn researchers find that the anesthetic and fast-acting antidepressant switches natural patterns of neuronal activity in the cerebral cortex.

From Penn Medicine News

For ‘spirit of innovation,’ three from Penn named National Academy of Inventors Fellows
Penn faculty Vijay Kumar, Katalin Kariko, and Drew Weissman

Vijay Kumar of Penn Engineering and Katalin Karikó and Drew Weissman of the Perelman School of Medicine have been named Fellows of the National Academy of Inventors, recognizing their contributions to inventions that have made a meaningful impact on society. (Images: Penn Engineering/Penn Medicine)

For ‘spirit of innovation,’ three from Penn named National Academy of Inventors Fellows

Vijay Kumar of the School of Engineering and Applied Science and Katalin Karikó and Drew Weissman of the Perelman School of Medicine were honored with the recognition.

Katherine Unger Baillie , Nathi Magubane , Alex Gardner

What the Twitter upheaval means to Penn health services researchers
A Twitter icon on the ground with a large crowd of people circling, as seen from above.

What the Twitter upheaval means to Penn health services researchers

LDI senior fellows weigh in on Twitter’s current upheaval, and whether they think the situation at the social media company will impact how they disseminate research in the future.

Hoag Levins

Abandoned house repairs reduced nearby gun violence
John MacDonald and Gina South in West Philly

John MacDonald of the Department of Criminology and Eugenia South of the Perelman School of Medicine.

Abandoned house repairs reduced nearby gun violence

Installing working windows and doors, cleaning trash, and weeding at abandoned houses led to safety improvements and should be considered in efforts to create healthy communities, according to researchers from University of Pennsylvania and Columbia.

Kelsey Geesler