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‘Trusted messengers’ distill science, debunk myths about COVID-19 vaccine
A person, Helaine Heggs, standing outside in front of a tree.

Helaine Heggs is one of 24 ambassadors recruited by VaxUpPhillyFamilies, an initiative spearheaded by Penn’s School of Nursing, in collaboration with the Annenberg School for Communication, Perelman School of Medicine, Children’s Hospital of Philadelphia, Philly Counts, and Konquered Healthcare Solutions. (Image: Linda Jiang)

‘Trusted messengers’ distill science, debunk myths about COVID-19 vaccine

VaxUpPhillyFamilies, led by Penn’s School of Nursing, engages Philadelphia parents and caregivers as vaccine ambassadors to identify concerns and provide support related to COVID-19 vaccines, increase vaccine uptake, and address social support needs.

Michele W. Berger

Losing mom to brain cancer fuels an expert’s mission for breakthrough
Gregory L. Beatty holds up a fluid sample in a lab setting.

Gregory L. Beatty, director of the Clinical and Translational Research Program with the Penn Pancreatic Cancer Research Center, lost his mother to brain cancer just weeks after her diagnosis.

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Losing mom to brain cancer fuels an expert’s mission for breakthrough

Research by Gregory L. Beatty, who lost his mother to glioblastoma, and colleagues have found that immunotherapy might have some activity in patients with relapsed tumors, and a potential target location for immunotherapy in glioblastoma tumors.

From Penn Medicine News

Penn Medicine’s 1,500th lung transplant
Garcia Bolton.

Garcia Bolton, a lifelong Philadelphian, received Penn Medicine’s 1500th lung transplant. (Image: Penn Medicine News)

Penn Medicine’s 1,500th lung transplant

The milestone transplant helped give new life to Garcia Bolton, a father, truck driver, poet, and lifelong Philadelphian.

Alex Gardner

Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors
four panels show a cancerous tumor with some portions labeled in red, green, and blue, and a close up image of part of it

The researchers found that levels of phosphorylated HRS varied across tumors, negatively corresponding with the level of T cell infiltration in those areas. (Image: Guo lab/Nature Communications)

Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors

Biologist Wei Guo and colleagues elucidate the process of sorting and loading cargo for these biological drones with implications for a more targeted and effective use of checkpoint inhibitor drugs in cancer treatment.

Katherine Unger Baillie

Can nature-inspired designs affect cognition and mood?
Farhan Jivraj sits at a desk and looks at the topographic rug in the biophilic room

Can nature-inspired designs affect cognition and mood?

A team from the Center for Neuroaesthetics created a biophilic room to test the idea. Preliminary findings from a small pilot show promise, but also spur many questions about how to best use such a space.

Michele W. Berger , Kelsey Geesler , Michael Grant

New evidence suggests human brain produces immature neurons throughout lifespan
Microscopic view of illuminated brain neurons.

New evidence suggests human brain produces immature neurons throughout lifespan

Work from Perelman School of Medicine and elsewhere found these neurons in significant numbers in the hippocampus. The findings pave the way for the deeper study of the role this neuron formation plays in memory, mood, behavior, and brain disorders.

Where and when violent crime rates fall, heart disease deaths fall, too
Chicago city skyline.

Researchers from the Perelman School of Medicine evaluated 15 years of data gathered from the city of Chicago for their study.

Where and when violent crime rates fall, heart disease deaths fall, too

A study of data from Chicago by Perelman School of Medicine researchers revealed that, as violent crime decreases, so does the area’s death rate from heart disease.

From Penn Medicine News

‘Stop the Bleed’ program helps bystanders in India aid accident victims
A group of men in India stand in a line holding first aid kits and certificates

Participants in the A-B-C Stop the Bleed program hold their first aid kits and certificates of training in the Kalakal neighborhood, outside Hyderabad, India. (Image: Courtesy of A-B-C Stop the Bleed)

‘Stop the Bleed’ program helps bystanders in India aid accident victims

The innovative program addresses the country’s high rate of preventable fatalities by offering training on how to recognize and stop life-threatening bleeding.

Kristen de Groot

The economic impact of rural hospital closures
Two vehicles parked outside the Harris Sub-Regional Clinic in Alaska

The economic impact of rural hospital closures

A study led by Paula Chatterjee and colleagues shows that rural hospital closures reflect existing economic downturns in communities and economies that were already declining before the hospital shut its doors.

From Penn LDI