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Racial disparity in follow-up appointments disappears with telemedicine
A patient having a telemedicine appointment with a doctor via a desktop computer screen.

Racial disparity in follow-up appointments disappears with telemedicine

An inequity in the rate of Black patients making it to their primary care appointment after a hospitalization was eliminated after telemedicine became widely used amid the COVID-19 pandemic.

From Penn Medicine News

Busting myths about the Asian American ‘model minority’
Patient with a face mask looking at a computer with a medical professional.

Busting myths about the Asian American ‘model minority’

Two new studies highlight the problem with aggregating diverse groups of people into a single category of “Asian American” when applied to cardiovascular disease and cancer diagnosis and outcomes.

From Penn LDI

A new method to increase effectiveness of nanomedicines
Microscopic view of nanomedicine particles attacked by immune system proteins.

Upon injection into the blood, nanomedicines (blue spheres) are immediately attacked by proteins of the immune system called complement proteins (orange). Complement proteins cause rapid destruction of the nanomedicine, and also induce an anaphylaxis-like reaction. By attaching complement-degrading proteins (yellow ninjas made of protein) to the surface of nanomedicines, Penn researchers have largely solved this problem, potentially allowing more diseases to be safely treated by nanomedicine.(Image: Penn Medicine News)

A new method to increase effectiveness of nanomedicines

Penn Medicine researchers have developed a new technique that uses complement inhibitor Factor I to prevent proteins from attacking treatment-carrying nanoparticles so they can better reach targets within the body.

Sophie Kluthe

Protein controlled by both light and temperature can inform cell signal pathways
Microscopic view of cells illuminated by light.

Protein controlled by both light and temperature can inform cell signal pathways

Penn Engineering researchers have described a new type of optogenetic protein that can be controlled not only by light, but also by temperature, allowing for a higher degree of control in the manipulation of cellular pathways.

From Penn Engineering Today

Researchers find new potential targets for skin-cancer treatment
Microscopic view of skin tissue cells.

Researchers find new potential targets for skin-cancer treatment

Making up for the genetic mutations of MLL4 in skin cells, one of the most commonly mutated genes across all of human cancers, may keep epithelial cancer from beginning and progressing

Alex Gardner

Catching up with omicron
Microscopic view of numerous particles of SARS-CoV-2 labeled blue emerging from an infected cell.

Particles of SARS-CoV-2, the virus that causes COVID-19, emerged from a cell infected in a lab. Researchers and clinicians at Penn and around the world have turned their attention to omicron, a recently emerged variant that is sweeping through the population. (Image: National Institute of Allergy and Infectious Diseases)

Catching up with omicron

The Perelman School of Medicine’s Frederic Bushman and Susan Weiss share what they and other scientists are learning about the new, dominant variant of SARS-CoV-2.

Katherine Unger Baillie

A structural blueprint of nanoparticles to target acute lung inflammation
X-ray of lungs illuminated in red.

A structural blueprint of nanoparticles to target acute lung inflammation

Targeting neutrophils, a type of white blood cell that, when overactive, contributes to acute lung inflammation, is a potential new route to diagnose and treat acute respiratory distress syndrome.

From Penn Medicine News