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Penn Research Using Frog Embryos Leads to New Understanding of Cardiac Development

Penn Research Using Frog Embryos Leads to New Understanding of Cardiac Development

PHILADELPHIA—During embryonic development, cells migrate to their eventual location in the adult body plan and begin to differentiate into specific cell types. Thanks to new research at the University of Pennsylvania, there is new insight into how these processes regulate tissues formation in the heart.

Evan Lerner

Penn Research Identifies Potential Mechanisms for Future Anti-Obesity Drugs

Penn Research Identifies Potential Mechanisms for Future Anti-Obesity Drugs

PHILADELPHIA — An interdisciplinary group of researchers at the University of Pennsylvania has, for the first time, identified the neurological and cellular signaling mechanisms that contribute to satiety — the sensation of feeling full — and the subsequent body-weight loss produced by drugs used to treat type 2 diabetes.

Evan Lerner

Penn Scientists Identify New Role for Protein Molecule That Inhibits Response of Immune-System Cells

Penn Scientists Identify New Role for Protein Molecule That Inhibits Response of Immune-System Cells

           PHILADELPHIA -– Researchers at the University of Pennsylvania have identified a new role for a protein molecule that inhibits the response of immune-system cells to inflammatory signals associated with many human diseases.           

Jacquie Posey

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

PHILADELPHIA –- A study comparing a University of Pennsylvania method for evaluating a dog’s susceptibility to hip dysplasia to the traditional American method has shown that 80 percent of dogs judged to be normal by the traditional method are actually at risk for developing osteoarthritis and hip dysplasia, according to the Penn method.

Jacquie Posey

Researchers Find Clues to Gut Immunity Evolution, Reveal Similarities Between Fish/Humans

Researchers Find Clues to Gut Immunity Evolution, Reveal Similarities Between Fish/Humans

PHILADELPHIA  -– A study at the University of Pennsylvania School of Veterinary Medicine has identified the function of one of the earliest antibodies in the animal kingdom, an ancient immunoglobulin that helps explain the evolution of human intestinal immune responses.  It was discovered to play a predominant role in the guts of fish and paves

Jordan Reese

Collaboration Solves Structure of Herpes Virus Protein, Provides New Drug Directions

Collaboration Solves Structure of Herpes Virus Protein, Provides New Drug Directions

PHILADELPHIA  -– The mechanism by which a herpes virus invades cells has remained a mystery to scientists, but now research from Tufts University and the University of Pennsylvania reveals the unusual structure of a key member of the protein complex that allows a herpes virus to invade cells.

Jordan Reese

Gene Therapy Success Sets Stage for New Treatments for Inherited Blindness, Penn Veterinary Researchers Say

Gene Therapy Success Sets Stage for New Treatments for Inherited Blindness, Penn Veterinary Researchers Say

PHILADELPHIA –- Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.  

Jordan Reese