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Penn Scientists Identify New Role for Protein Molecule That Inhibits Response of Immune-System Cells

Penn Scientists Identify New Role for Protein Molecule That Inhibits Response of Immune-System Cells

           PHILADELPHIA -– Researchers at the University of Pennsylvania have identified a new role for a protein molecule that inhibits the response of immune-system cells to inflammatory signals associated with many human diseases.           

Jacquie Posey

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

PHILADELPHIA –- A study comparing a University of Pennsylvania method for evaluating a dog’s susceptibility to hip dysplasia to the traditional American method has shown that 80 percent of dogs judged to be normal by the traditional method are actually at risk for developing osteoarthritis and hip dysplasia, according to the Penn method.

Jacquie Posey

Researchers Find Clues to Gut Immunity Evolution, Reveal Similarities Between Fish/Humans

Researchers Find Clues to Gut Immunity Evolution, Reveal Similarities Between Fish/Humans

PHILADELPHIA  -– A study at the University of Pennsylvania School of Veterinary Medicine has identified the function of one of the earliest antibodies in the animal kingdom, an ancient immunoglobulin that helps explain the evolution of human intestinal immune responses.  It was discovered to play a predominant role in the guts of fish and paves

Jordan Reese

Collaboration Solves Structure of Herpes Virus Protein, Provides New Drug Directions

Collaboration Solves Structure of Herpes Virus Protein, Provides New Drug Directions

PHILADELPHIA  -– The mechanism by which a herpes virus invades cells has remained a mystery to scientists, but now research from Tufts University and the University of Pennsylvania reveals the unusual structure of a key member of the protein complex that allows a herpes virus to invade cells.

Jordan Reese

Gene Therapy Success Sets Stage for New Treatments for Inherited Blindness, Penn Veterinary Researchers Say

Gene Therapy Success Sets Stage for New Treatments for Inherited Blindness, Penn Veterinary Researchers Say

PHILADELPHIA –- Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.  

Jordan Reese

Gene Therapy Cures Canines of Inherited Form of Day Blindness, Penn Veterinary Researchers Say

Gene Therapy Cures Canines of Inherited Form of Day Blindness, Penn Veterinary Researchers Say

PHILADELPHIA –- Veterinary ophthalmology researchers from the University of Pennsylvania have used gene therapy to restore retinal cone function and day vision in two canine models of congenital achromatopsia, also called rod monochromacy or total color blindness.

Jordan Reese