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Bioengineering
Novel tools for the treatment and diagnosis of epilepsy
Novel tools for the treatment and diagnosis of epilepsy
Penn neurologist Brian Litt’s work on implantable devices for recording and altering brain activity has led to new ways to treat and diagnose epilepsy.
Gregory Bowman appointed Penn Integrates Knowledge University Professor
Gregory Bowman appointed Penn Integrates Knowledge University Professor
The pioneer of biophysics and data science has joint appointments in the Department of Biochemistry and Biophysics in the Perelman School of Medicine and the Department of Bioengineering in the School of Engineering and Applied Science.
More cancers may be treated with drugs than previously believed
More cancers may be treated with drugs than previously believed
Using a Penn-designed neural network called PocketMiner, a Penn Medicine research team has identified hidden protein pockets that can provide new opportunities for cancer drugs to bind to.
A potential strategy to improve T cell therapy in solid tumors
A potential strategy to improve T cell therapy in solid tumors
A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.
Targeted prenatal therapy addresses long-standing gap in health equity
Targeted prenatal therapy addresses long-standing gap in health equity
Penn engineers have developed a successful delivery system of mRNA to placental cells to treat preeclampsia at its root.
New insights into the mechanisms of tumor growth
New insights into the mechanisms of tumor growth
A team of researchers led by the School of Arts & Science’s Wei Guo characterize the molecular pathways that play a major role in tumorigenesis, findings that could lead to better diagnostic tools for cancer and new targeted therapies.
RNA lipid nanoparticle engineering stops liver fibrosis in its tracks
RNA lipid nanoparticle engineering stops liver fibrosis in its tracks
A successful lipid nanoparticles drug delivery system targets notoriously hard-to-target activated fibroblasts in the liver.
OCTOPUS, an optimized device for growing mini-organs in a dish
OCTOPUS, an optimized device for growing mini-organs in a dish
With OCTOPUS, Dan Huh’s team expands organoid research with a platform superior to conventional gel droplets, allowing researchers to replicate biological systems outside of the body.
New cell characterization method hints at reasons for resistance to cancer therapies
New cell characterization method hints at reasons for resistance to cancer therapies
Penn experts have developed new analysis tool that combines a cell’s unique gene expression data with information about the cell’s origins. The method can be applied to identify new cell subsets throughout development and better understand drug resistance.
Penn Libraries dedicates Holman Biotech Commons
Penn Libraries dedicates Holman Biotech Commons
The Commons serves as a collaborative resource for researchers in the health sciences, providing the latest tools and technologies to further health care research and equality.
In the News
HealthDay
In mouse studies, new hope against a dangerous complication of pregnancy
Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication.
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New Scientist
Pre-eclampsia could be treated with mRNA technology
Michael Mitchell and Ph.D. student Kelsey Swingle of the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication.
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Axios
Real vs. fake Christmas trees: The great debate, explained
Lorena Grundy of the School of Engineering and Applied Science says that the debate between real and fake Christmas trees isn’t as black and white as it’s being portrayed.
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Rolling Stone
RFK Jr.’s 10 wildest medical theories
Kenneth R. Foster of the School of Engineering and Applied Science says studies haven’t provided clear evidence that exposure to levels of radio frequency energy below accepted limits, such as Wi-Fi, disrupts the blood-brain barrier.
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Nature
Gut microbes’ genomes are a trove of potential antibiotics
Marcelo Torres of the School of Engineering and Applied Science and colleagues are synthesizing antibiotic microbes from microbiomes in the human gut.
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Pittsburgh Post-Gazette
Smart meter debate: Small group of consumers pushes against a meter mandate in Pennsylvania
Kenneth Foster of the School of Engineering and Applied Science says that the most reliable conclusions are always those of expert panels that conduct systematic reviews according to established procedures.
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