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Biology

Rewiring cell division to make eggs and sperm
Images of two cells undergoing division with purple and blue labels

New findings reveal the varied roles of a key protein in cell division. When the protein Meikin is not properly cleaved before meiosis II, chromosomes do not align properly, causing problems in cell division (bottom image). Chromosomes are in blue and the cellular machinery that pulls them to opposite sides of the cell is in purple. (Image: Jun Ma)

Rewiring cell division to make eggs and sperm

Research by the School of Arts & Sciences’ Michael Lampson and Jun Ma, collaborating with Whitehead Institute researchers, reveals how a key protein enables the process of meiosis to unfold.

Katherine Unger Baillie

High-ranking hyena mothers pass their social networks to their cubs
Group of hyenas on the landscape

Hyenas benefit from being born to high-ranking mothers, from whom they inherit their social networks, according to research led by biologists from Penn and Michigan State University. (Image: Kate Shaw Yoshida)

High-ranking hyena mothers pass their social networks to their cubs

Using 27 years of detailed data on hyena social interactions, a team led by Penn biologists nailed down a pattern of social network inheritance and its implications for social structure, rank, and survival.

Katherine Unger Baillie

Obscuring the truth can promote cooperation
Businesspeople shaking hands holding up masks to their faces

Obscuring the truth can promote cooperation

People are more likely to cooperate if they think others are cooperating, too. New research by biologists in the School of Arts & Sciences shows that overstating the true level of cooperation in a society can increase cooperative behavior overall.

Katherine Unger Baillie

Protein’s ‘silent code’ affects how cells move
six panels showing cells in green with protein involved in cell movement labeled in red

Protein’s ‘silent code’ affects how cells move

A School of Veterinary Medicine-led study shows how, despite having nearly identical amino acid sequences, two forms of the protein actin differ in function due their distinct nucleotide sequences.

Katherine Unger Baillie

With remarkable similarities to MS, a disease in dogs opens new avenues for study
Microscopic image of cells labeled blue, green, and pink

A naturally occurring canine disease called granulomatous meningoencephalomyelitis replicates many features of multiple sclerosis, including the involvement of B cells (in red) and T cells (green) in the tissues that line the central nervous system. (Image: Penn Vet)

With remarkable similarities to MS, a disease in dogs opens new avenues for study

Researchers at the School of Veterinary Medicine led by Jorge Iván Alvarez and Molly Church found that the canine disease granulomatous meningoencephalomyelitis shares many of the same pathological and immunological features as MS.

Katherine Unger Baillie

Ballerina Emily Davis is ‘on her toes’
Ballerina Emily Davis completed her Penn degree while dancing with the Pennsylvania Ballet.

May graduate Emily Davis earned a bachelor’s degree in biology from the College of Liberal and Professional Studies while working full-time as a ballerina with the Pennsylvania Ballet and volunteering to conduct research at CHOP and community service with Philadelphia nonprofits. (Image: Arian Molina Soca)

Ballerina Emily Davis is ‘on her toes’

May graduate Emily Davis earned a bachelor’s degree in biology from the College of Liberal and Professional Studies while working full-time as a ballerina with the Pennsylvania Ballet and volunteering to conduct research at CHOP and community service with Philadelphia nonprofits.
Designing public institutions that foster cooperation
wooden blocks with a person icon shown connected by a web

Designing public institutions that foster cooperation

People are more likely to cooperate with those they see as “good.” Using a mathematical model, School of Arts & Sciences researchers found it’s possible to design systems that assess and broadcast participants’ reputations, leading to high levels of cooperation and adherence.

Katherine Unger Baillie