Through
4/26
Cancer Research
Researchers unlock the door to tumor microenvironment for CAR T cells
Researchers unlock the door to tumor microenvironment for CAR T cells
A new study finds that combining CAR T thereapy with an enzyme-inhibitor drug allows the engineered cells to battle through jumbled blood vessels and attack tumors.
Donita Brady is ready for the next steps in cancer biology research
Donita Brady is ready for the next steps in cancer biology research
The Presidential Professor of cancer biology leads a team that is working to understand how cancer grows uncontrolled in cells and discovering novel ways to stop it.
Diagnostic imaging may increase risk of testicular cancer
Diagnostic imaging may increase risk of testicular cancer
New research shows a statistically significant increased risk of testicular cancer among those reporting at least three exposures to X-ray, including a colon X-ray, and CT below the waist.
Two key events that turn normal cells into cancer
Two key events that turn normal cells into cancer
The discovery of a unifying mechanism could inform new therapeutic approaches to prevent normal cells from transforming into any type of tumor.
‘Fast’ MRI detects breast cancers that 3-D mammograms may miss
‘Fast’ MRI detects breast cancers that 3-D mammograms may miss
Abbreviated MRI shortens the screening time and requires only three sequences, while traditional ultrasound’s limitations don’t detect cancer as reliably for women with higher breast density.
Priming the immune system to attack cancer
Priming the immune system to attack cancer
An international team, co-led by the School of Dental Medicine’s George Hajishengallis, showed how immune “training” transforms certain immune cells to target tumors.
Nudges and machine learning triples advanced care conversations
Nudges and machine learning triples advanced care conversations
During the pandemic, a Penn-developed algorithm helped sustain end-of-life care discussions with patients with cancer.
Anthony Fauci and Penn Medicine physicians on cancer care during pandemic
Anthony Fauci and Penn Medicine physicians on cancer care during pandemic
A virtual conference on cancer and COVID-19 discussed how medical professionals adapt to a rapidly changing environment and enforce protocols to deliver care safely, while individuals are choosing to skip cancer screenings or delay treatments.
Avery Posey’s cancer research takes high risks for big rewards
Avery Posey’s cancer research takes high risks for big rewards
The assistant professor of systems pharmacology and translational therapeutics, who studied with Carl June as a postdoctoral fellow, combines his two research passions—gene therapy and investigating ‘little known’ biology—in the pursuit of new knowledge.
‘Self-eating’ stem cell process may be the key to new regenerative therapies
‘Self-eating’ stem cell process may be the key to new regenerative therapies
A Penn study uncovers new roles of chaperone-mediated autophagy in how stem cells repair or regenerate damaged organs.
In the News
CNN
There’s still no standard test to detect pancreatic cancer early. Scientists are working to change that
A 2020 study from the Perelman School of Medicine found that a blood test to screen for certain biomarkers associated with pancreatic cancer was 92% accurate in its ability to detect disease.
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Associated Press
A new strategy to attack aggressive brain cancer shrank tumors in two early tests
A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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Philadelphia Inquirer
Penn’s BRCA cancer vaccine trial aims to prevent the disease in healthy people
A trial led by Susan Domchek of the Perelman School of Medicine could use a preventive vaccine to protect people with a BRCA gene mutation from cancer.
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Philadelphia Inquirer
UPenn scientists among those developing vaccines that arm the immune system to fight cancer
Penn Medicine researchers like Nobel laureate Drew Weissman are leading efforts to develop a vaccine that prevents cancer, with remarks from Susan Domchek of the Basser Center for BRCA and Robert H. Vonderheide of the Abramson Cancer Center.
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Psychology Today
AI detects cancers and immunotherapy biomarker
Daiwei Zhang and Mingyao Li of the Perelman School of Medicine and colleagues have developed an AI tool called iStar that can automatically spot tumors and types of cancer that are difficult for clinicians to see or identify and can predict candidates for immunotherapy.
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Philadelphia Inquirer
Penn started giving cancer patients free rides to appointments. It helped reduce no-shows and increase clinical trial enrollment
The Abramson Cancer Center is attempting to address one of the most common challenges cancer patients face: lack of transportation to critically important appointments. Robert Vonderheide and Carmen Guerra of the Perelman School of Medicine are quoted on the Ride Health initiative.
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