Cancer Research | Penn Today

Understanding the needs of cancer care partners

Through the Penn Undergraduate Research Mentoring Program, undergrads Abi Ocholi and Akin Adio deepened their understanding of qualitative research and of the experiences of caregivers.

J. Larry Jameson, Susan Domcheck, Liz Magill, Mindy Gray, and Jon Gray in front of a sign that reads Basser Center for BRCA.

$55M gift creates new ‘Cancer Interception’ Institute at Penn’s Basser Center for BRCA to stop hereditary cancers at the earliest stages

Funding for the Institute from Mindy and Jon Gray will propel early detection and prevention of breast, ovarian, pancreatic, and prostate cancers.

Blackstone’s Gray gives UPenn $55 million for cancer prevention

Alums Mindy and Jon Gray are funding the Basser Institute for Cancer Interception to focus on early detection and prevention of breast, ovarian, pancreatic, and prostate cancers.

$55 million gift to Penn is aimed at stopping breast cancer before it starts

Mindy and Jon Gray’s new Basser Institute is a spinoff of their previously funded Basser Center for BRCA, named for Mindy’s late sister Faith Basser and led by Susan Domchek of the Perelman School of Medicine.

Cell-killing cancer therapy shows promise for a devastating autoimmune disorder

Aimee Payne of the Perelman School of Medicine says that the University of Erlangen-Nürnberg’s new CAR-T therapy lupus research represents a landmark study in the treatment of autoimmunity.

Penn spinout Capstan Therapeutics launches with $165M and an all-star lineup of founders

Capstan Therapeutics, a Penn spinout whose founders include Carl June, Bruce Levine, and Drew Weissman of the Perelman School of Medicine, has launched with $165 million raised to develop a new type of CAR therapy that incorporates mRNA.

Fluorescent microscopic image of three T cells surrounding a cancer cell

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response

Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.

A doctor checks a person’s arm for melanoma with a hand-held scanning device.

Potential new therapeutic targets to treat melanoma

Penn Medicine research shows that a relative lack of DOPA, and not simply susceptibility to sun damage, helps explain why melanoma is much more common in people with light skin tones.

Personalized immunotherapy shows promise beyond cancer

Carl June of the Perelman School of Medicine is interviewed on the use of customized immunotherapy to treat new blood cancers, as well as its potential for treating solid state cancers and autoimmune diseases.

Gregory L. Beatty holds up a fluid sample in a lab setting.

Losing mom to brain cancer fuels an expert’s mission for breakthrough

Research by Gregory L. Beatty, who lost his mother to glioblastoma, and colleagues have found that immunotherapy might have some activity in patients with relapsed tumors, and a potential target location for immunotherapy in glioblastoma tumors.

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