Cancer Research

In what could be a ‘big shift’ for cancer treatment, mRNA vaccine shows promise against melanoma

According to Robert Vonderheide of the Perelman School of Medicine, the pandemic proved that mRNA vaccines could be used safely and developed quickly.

Novel treatment shows promise against rare cancer in kids

Carl June of the Perelman School of Medicine comments on the success of a new study using CAR-T cell therapy to combat tumors in children with a rare kind of cancer.

More cancers may be treated with drugs than previously believed

Using a Penn-designed neural network called PocketMiner, a Penn Medicine research team has identified hidden protein pockets that can provide new opportunities for cancer drugs to bind to.

T cells therapy in solid tumors shows improvement

A preclinical study by researchers at the Perelman School of Medicine is using a novel “one-two punch” strategy to assist T cells in attacking solid tumors.

A potential strategy to improve T cell therapy in solid tumors

A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.

A doctor and patient seated at a desk having a consultation.

A moment for men’s health

Since 2012, the Basser Center for BRCA at Penn Medicine’s Abramson Cancer Center has been advancing lifesaving therapies and raising awareness of the risks faced by individuals with BRCA gene mutations.

A chart showing the intersection of a cell as it changes from pre-cancer to cancer stage one and two.

Can we intercept cancer?

Penn researchers are developing new ways to detect and “intercept” cancer from every angle, including basic science to understand the molecular changes that lead to cancer and developing new methods for finding it.

New insights into the mechanisms of tumor growth

A team of researchers led by the School of Arts & Science’s Wei Guo characterize the molecular pathways that play a major role in tumorigenesis, findings that could lead to better diagnostic tools for cancer and new targeted therapies.

A banner hanging outside in a small town in Lebanon.

From a small town in Lebanon to cancer research

When Mayassa Bou-Dargham, a postdoctoral fellow in Penn’s Abramson Family Cancer Research Institute received a pilot project grant, a banner was hung in her Lebanese hometown. Getting there took years of determination, self-confidence and, in small part, fate.

Doctor in lab pointing to ultrasound images of a uterus.

How one doctor-patient relationship could change how women are treated for gynecologic cancers

In appreciation for her cancer treatment team led by Neil Taunk, patient Dalia Jakas established a fund to empower Taunk’s research into how treatment can be improved for uterine cancers like the one she experienced.

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