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Coronavirus Research

A scientific hunch. Then silence. Until the world needed a lifesaving vaccine

A scientific hunch. Then silence. Until the world needed a lifesaving vaccine

Drew Weissman of the Perelman School of Medicine was profiled in a series of articles about the scientists who helped create the COVID-19 vaccines. “The person who achieves his goal is the one that has faced frustration and dealt with it, understood it, and used it to their advantage,” Weissman said.

A one-way ticket. A cash-stuffed teddy bear. A dream decades in the making

A one-way ticket. A cash-stuffed teddy bear. A dream decades in the making

Katalin Karikó of the Perelman School of Medicine was profiled in a series of articles about the scientists who helped create the COVID-19 vaccines. “I think she should be given credit for saving the world,” said her colleague Jean Bennett. Karikó’s ideas were “so ahead of her time, she had a hard time convincing people that they would actually work,” Bennett said. “They seemed too science fiction-y to people and too challenging.”

Philadelphia doctor develops rapid COVID test with results on smartphone

Philadelphia doctor develops rapid COVID test with results on smartphone

A team of researchers led by Ping Wang of the Perelman School of Medicine is developing a more accurate rapid test for COVID-19 that uses smart phone cameras. “The PCR is great. It's sensitive, but at the same time it's only residing in the core laboratories,” she said. “So, you can't really do PCR at home for most settings.”

Drew Weissman and Katalin Karikó receive 2021 Lasker Award
Drew Weisman and Katalin Kariko wear masks in a lab and look at liquid in a test tube.

mRNA scientists Drew Weissman, the Roberts Family Professor of Vaccine Research in Penn’s Perelman School of Medicine, and Katalin Karikó, an adjunct professor of neurosurgery at Penn and a senior vice president at BioNTech. (Image: Courtesy of Penn Medicine)

Drew Weissman and Katalin Karikó receive 2021 Lasker Award

Weissman and Karikó’s mRNA technology is recognized for enabling rapid development of highly effective COVID-19 vaccines

Alex Gardner

2022 Breakthrough Prize in Life Sciences awarded to mRNA pioneers Drew Weissman and Katalin Karikó
Drew Weissman and Katalin Karikó standing side by side.

Twenty-five years ago, Drew Weissman and Katalin Karikó struck up their first conversations at Penn by a copy machine, where both were printing journal articles. That chance encounter laid the foundation for a revolution in mRNA technology, innovations that are now being leveraged to confront a host of biomedical challenges. (Image: Peggy Peterson)

2022 Breakthrough Prize in Life Sciences awarded to mRNA pioneers Drew Weissman and Katalin Karikó

Weissman and Karikó are honored for engineering modified RNA technology which enabled rapid development of effective COVID-19 vaccines.

Alex Gardner

Penn scientists win $3 million Breakthrough Prize for RNA research that enabled COVID-19 vaccines

Penn scientists win $3 million Breakthrough Prize for RNA research that enabled COVID-19 vaccines

Katalin Karikó and Drew Weissman of the Perelman School of Medicine have been awarded a $3 million Breakthrough Prize for research that paved the way for COVID-19 vaccines. “It’s been very wonderful,” said Weissman. “I never thought it was possible.”