Study of gender-affirming care reveals immune system sex differences Penn In the News Stat Study of gender-affirming care reveals immune system sex differences Montserrat Anguera of the Perelman School of Medicine and the School of Veterinary Medicine comments on the work to comprehensively examine the impact of gender-affirming care on the immune system. Uncovering new antibiotics inside the human gut Image: iStock/ChrisChrisW Uncovering new antibiotics inside the human gut Researchers from Penn Engineering, led by César de la Fuente, have leveraged AI to discover dozens of potential new antibiotics in the human gut microbiome. A disease that makes children age rapidly gets closer to a cure Penn In the News The New York Times A disease that makes children age rapidly gets closer to a cure Kiran Musunuru of the Perelman School of Medicine says there’s no guarantee that gene editing which worked well in mice will also work with human patients. She’s fighting to stop the brain disease that killed her mother before it gets her Penn In the News USA Today She’s fighting to stop the brain disease that killed her mother before it gets her Kiran Musunuru of the Perelman School of Medicine comments on shutting off genetic signals in the brain to hold off diseases. Rare disease’s DNA-damaging mutation could have consequences for more common conditions Image: iStock/piyaset Rare disease’s DNA-damaging mutation could have consequences for more common conditions In their pursuit to discover the mechanism behind how the deadly rare disease RVCL does its damage, Penn Medicine researchers found some clues to the DNA damage theory of aging. How deadly parasites choose to be male Penn Vet researchers developed the Cryptosporidium single-cell atlas, revealing which genes are expressed at which points across the parasite’s life cycle. On the left, the atlas shows parasites replicating asexually in green, with males in blue and females in pink. On the right, micrographs of the stages are shown, with their nuclei highlighted in green.(Image: Boris Striepen) How deadly parasites choose to be male Penn Vet researchers reveal the gene expression across the life cycle of Cryptosporidium and identify the determinant of maleness. Scientists discover a key quality-control mechanism in DNA replication Illustration of the 55LCC complex. (Image: Courtesy of Cameron Baines/Phospho Biomedical Animation) Scientists discover a key quality-control mechanism in DNA replication New research from Penn Medicine advances the understanding of DNA replication and could have relevance for neurologic diseases and other conditions. A novel technique to form human artificial chromosomes Image: iStock/Mohammed Haneefa Nizamudeen A novel technique to form human artificial chromosomes Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research. Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry Image: iStock/DragonImages Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry A Penn Medicine analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma. Two-and-a-half decades of research in Malawi Collaborators on the Malawi Longitudinal Study of Families and Health visited the University of Pennsylvania in October for a project meeting. Pictured are Lauren Schmitz (University of Wisconsin-Madison), Namrata Ray (Penn), Hans-Peter Kohler (Penn), Kondwani Katundu (Kamuzu University of Health Sciences in Malawi), Kazione Kulisewa (Kamuzu University), Iliana V. Kohler (Penn), and Victor Mwapasa (Kamuzu University).(Image: Eric Sucar) Two-and-a-half decades of research in Malawi As the country’s life expectancy has risen, the Malawi Longitudinal Study of Families and Health has shifted its current and future research to aging. Load More
Uncovering new antibiotics inside the human gut Image: iStock/ChrisChrisW Uncovering new antibiotics inside the human gut Researchers from Penn Engineering, led by César de la Fuente, have leveraged AI to discover dozens of potential new antibiotics in the human gut microbiome.
A disease that makes children age rapidly gets closer to a cure Penn In the News The New York Times A disease that makes children age rapidly gets closer to a cure Kiran Musunuru of the Perelman School of Medicine says there’s no guarantee that gene editing which worked well in mice will also work with human patients. She’s fighting to stop the brain disease that killed her mother before it gets her Penn In the News USA Today She’s fighting to stop the brain disease that killed her mother before it gets her Kiran Musunuru of the Perelman School of Medicine comments on shutting off genetic signals in the brain to hold off diseases. Rare disease’s DNA-damaging mutation could have consequences for more common conditions Image: iStock/piyaset Rare disease’s DNA-damaging mutation could have consequences for more common conditions In their pursuit to discover the mechanism behind how the deadly rare disease RVCL does its damage, Penn Medicine researchers found some clues to the DNA damage theory of aging. How deadly parasites choose to be male Penn Vet researchers developed the Cryptosporidium single-cell atlas, revealing which genes are expressed at which points across the parasite’s life cycle. On the left, the atlas shows parasites replicating asexually in green, with males in blue and females in pink. On the right, micrographs of the stages are shown, with their nuclei highlighted in green.(Image: Boris Striepen) How deadly parasites choose to be male Penn Vet researchers reveal the gene expression across the life cycle of Cryptosporidium and identify the determinant of maleness. Scientists discover a key quality-control mechanism in DNA replication Illustration of the 55LCC complex. (Image: Courtesy of Cameron Baines/Phospho Biomedical Animation) Scientists discover a key quality-control mechanism in DNA replication New research from Penn Medicine advances the understanding of DNA replication and could have relevance for neurologic diseases and other conditions. A novel technique to form human artificial chromosomes Image: iStock/Mohammed Haneefa Nizamudeen A novel technique to form human artificial chromosomes Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research. Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry Image: iStock/DragonImages Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry A Penn Medicine analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma. Two-and-a-half decades of research in Malawi Collaborators on the Malawi Longitudinal Study of Families and Health visited the University of Pennsylvania in October for a project meeting. Pictured are Lauren Schmitz (University of Wisconsin-Madison), Namrata Ray (Penn), Hans-Peter Kohler (Penn), Kondwani Katundu (Kamuzu University of Health Sciences in Malawi), Kazione Kulisewa (Kamuzu University), Iliana V. Kohler (Penn), and Victor Mwapasa (Kamuzu University).(Image: Eric Sucar) Two-and-a-half decades of research in Malawi As the country’s life expectancy has risen, the Malawi Longitudinal Study of Families and Health has shifted its current and future research to aging. Load More
She’s fighting to stop the brain disease that killed her mother before it gets her Penn In the News USA Today She’s fighting to stop the brain disease that killed her mother before it gets her Kiran Musunuru of the Perelman School of Medicine comments on shutting off genetic signals in the brain to hold off diseases. Rare disease’s DNA-damaging mutation could have consequences for more common conditions Image: iStock/piyaset Rare disease’s DNA-damaging mutation could have consequences for more common conditions In their pursuit to discover the mechanism behind how the deadly rare disease RVCL does its damage, Penn Medicine researchers found some clues to the DNA damage theory of aging. How deadly parasites choose to be male Penn Vet researchers developed the Cryptosporidium single-cell atlas, revealing which genes are expressed at which points across the parasite’s life cycle. On the left, the atlas shows parasites replicating asexually in green, with males in blue and females in pink. On the right, micrographs of the stages are shown, with their nuclei highlighted in green.(Image: Boris Striepen) How deadly parasites choose to be male Penn Vet researchers reveal the gene expression across the life cycle of Cryptosporidium and identify the determinant of maleness. Scientists discover a key quality-control mechanism in DNA replication Illustration of the 55LCC complex. (Image: Courtesy of Cameron Baines/Phospho Biomedical Animation) Scientists discover a key quality-control mechanism in DNA replication New research from Penn Medicine advances the understanding of DNA replication and could have relevance for neurologic diseases and other conditions. A novel technique to form human artificial chromosomes Image: iStock/Mohammed Haneefa Nizamudeen A novel technique to form human artificial chromosomes Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research. Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry Image: iStock/DragonImages Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry A Penn Medicine analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma. Two-and-a-half decades of research in Malawi Collaborators on the Malawi Longitudinal Study of Families and Health visited the University of Pennsylvania in October for a project meeting. Pictured are Lauren Schmitz (University of Wisconsin-Madison), Namrata Ray (Penn), Hans-Peter Kohler (Penn), Kondwani Katundu (Kamuzu University of Health Sciences in Malawi), Kazione Kulisewa (Kamuzu University), Iliana V. Kohler (Penn), and Victor Mwapasa (Kamuzu University).(Image: Eric Sucar) Two-and-a-half decades of research in Malawi As the country’s life expectancy has risen, the Malawi Longitudinal Study of Families and Health has shifted its current and future research to aging.
Rare disease’s DNA-damaging mutation could have consequences for more common conditions Image: iStock/piyaset Rare disease’s DNA-damaging mutation could have consequences for more common conditions In their pursuit to discover the mechanism behind how the deadly rare disease RVCL does its damage, Penn Medicine researchers found some clues to the DNA damage theory of aging.
How deadly parasites choose to be male Penn Vet researchers developed the Cryptosporidium single-cell atlas, revealing which genes are expressed at which points across the parasite’s life cycle. On the left, the atlas shows parasites replicating asexually in green, with males in blue and females in pink. On the right, micrographs of the stages are shown, with their nuclei highlighted in green.(Image: Boris Striepen) How deadly parasites choose to be male Penn Vet researchers reveal the gene expression across the life cycle of Cryptosporidium and identify the determinant of maleness.
Scientists discover a key quality-control mechanism in DNA replication Illustration of the 55LCC complex. (Image: Courtesy of Cameron Baines/Phospho Biomedical Animation) Scientists discover a key quality-control mechanism in DNA replication New research from Penn Medicine advances the understanding of DNA replication and could have relevance for neurologic diseases and other conditions.
A novel technique to form human artificial chromosomes Image: iStock/Mohammed Haneefa Nizamudeen A novel technique to form human artificial chromosomes Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research.
Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry Image: iStock/DragonImages Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry A Penn Medicine analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma.
Two-and-a-half decades of research in Malawi Collaborators on the Malawi Longitudinal Study of Families and Health visited the University of Pennsylvania in October for a project meeting. Pictured are Lauren Schmitz (University of Wisconsin-Madison), Namrata Ray (Penn), Hans-Peter Kohler (Penn), Kondwani Katundu (Kamuzu University of Health Sciences in Malawi), Kazione Kulisewa (Kamuzu University), Iliana V. Kohler (Penn), and Victor Mwapasa (Kamuzu University).(Image: Eric Sucar) Two-and-a-half decades of research in Malawi As the country’s life expectancy has risen, the Malawi Longitudinal Study of Families and Health has shifted its current and future research to aging.