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Immunology

Advances in cancer research
Microscopic rendering of interleukin 18 protein.

Interleukin-18 is a protein which in humans is encoded by the IL18 gene. “We designed an ‘armored’ CAR that secretes IL18 where we found it to have potent antitumor efficacy in our preclinical studies,” said Carl June. (Image: Penn Medicine News)

Advances in cancer research

Recent research shows promise in a novel CAR T therapy after cancer relapse, and a novel treatment for multiple myeloma.

From Penn Medicine News

CAR T cell therapy reaches beyond cancer
Cancer patient with IV drip and scarf on their hair looks out the window.

CAR T cell therapy reaches beyond cancer

Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies.

From Penn Medicine News