Immunology

This season’s flu and COVID-19 vaccines

Judith A. O’Donnell of the Perelman School of Medicine answers common questions about this year’s flu shot and the new COVID-19 vaccines.

Liana F. Wait

The immune health future, today

Breaking the code of the immune system could provide a new fundamental way of understanding, treating, and preventing every type of disease. Penn Medicine is investing in key discoveries about immunity and immune system function, and building infrastructure, to make that bold idea a reality.

Christina Hernandez Sherwood for Penn Medicine Magazine

An immunotherapy strategy against all blood cancers

Researchers at Penn Medicine have demonstrated a new potential treatment using CAR T cell therapy using a CRISPR base-editing to develop a method called “epitope editing.”

From Penn Medicine News

Carl June on the boundless potential of CAR T cell therapy

In a Q & A, June, the Richard W. Vague Professor in Immunotherapy, and Daniel Baker, a fourth-year doctoral student in Penn’s Cell and Molecular Biology department, discuss how the treatment can extend to treating diseases beyond cancer.

From Penn Medicine News

Putting biomedical research advances within reach

Treatments and vaccines are only useful in the hands of the people who need them, and Penn Medicine is working toward better access and equity for biomedical innovations.

Karen L. Brooks for Penn Medicine Magazine



In the News


RNZ/Radio New Zealand

Trial results offer hope to Kiwis with ‘incurable’ blood cancer

Carl June of the Perelman School of Medicine praises New Zealand research into a new CAR T-cell cancer treatment for patients with blood cancer.

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NPR

Long COVID brain fog may originate in a surprising place, say scientists

A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID’s neurological symptoms, like brain fog, memory loss, and fatigue, may stem from serotonin reduction.

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Time

Long COVID research is in its ‘most hopeful’ phase yet

A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that serotonin could be a target for long COVID treatment.

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ScienceAlert

A crucial pattern behind long COVID may have been identified

A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that several current hypotheses for the pathophysiology of long COVID are linked by a single pathway that is connected by serotonin reduction.

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WebMD

Study of serotonin levels offers hope for long COVID treatment

A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID is associated with lower levels of circulating serotonin, which could be relevant for its neurological, cognitive, and memory symptoms.

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WGN-TV

New research links symptoms of long COVID to serotonin levels—and more

A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues shows that long COVID can deplete peripheral serotonin levels, offering a baseline for treatment with serotonin supplementation.

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