Through
12/30
Immunology
Katalin Karikó and Drew Weissman, Penn’s historic mRNA vaccine research team, win 2023 Nobel Prize in Medicine
Katalin Karikó and Drew Weissman, Penn’s historic mRNA vaccine research team, win 2023 Nobel Prize in Medicine
The highest honor was bestowed for foundational discoveries that gave the world a vaccine to fight the COVID-19 pandemic.
An mRNA vaccine against Lyme disease-causing bacteria
An mRNA vaccine against Lyme disease-causing bacteria
In pre-clinical models, researchers at Penn Medicine have developed a vaccine that protects against Borrelia burgdorferi, the bacteria that causes Lyme disease.
This season’s flu and COVID-19 vaccines
This season’s flu and COVID-19 vaccines
Judith A. O’Donnell of the Perelman School of Medicine answers common questions about this year’s flu shot and the new COVID-19 vaccines.
The immune health future, today
The immune health future, today
Breaking the code of the immune system could provide a new fundamental way of understanding, treating, and preventing every type of disease. Penn Medicine is investing in key discoveries about immunity and immune system function, and building infrastructure, to make that bold idea a reality.
Removing the barrier surrounding solid tumors clears path for T cells
Removing the barrier surrounding solid tumors clears path for T cells
Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.
Penn Medicine’s Carl June to receive 2024 Breakthrough Prize in Life Sciences
Penn Medicine’s Carl June to receive 2024 Breakthrough Prize in Life Sciences
The Richard W. Vague Professor in Immunotherapy in the Perelman School of Medicine is honored for pioneering the development of CAR T cell therapy, which programs patients’ own immune cells to fight their cancer.
A suit of armor for cancer-fighting cells
A suit of armor for cancer-fighting cells
New research from the University of Pennsylvania offers a safer path for CAR T cell immunotherapy.
An immunotherapy strategy against all blood cancers
An immunotherapy strategy against all blood cancers
Researchers at Penn Medicine have demonstrated a new potential treatment using CAR T cell therapy using a CRISPR base-editing to develop a method called “epitope editing.”
Carl June on the boundless potential of CAR T cell therapy
Carl June on the boundless potential of CAR T cell therapy
In a Q & A, June, the Richard W. Vague Professor in Immunotherapy, and Daniel Baker, a fourth-year doctoral student in Penn’s Cell and Molecular Biology department, discuss how the treatment can extend to treating diseases beyond cancer.
Putting biomedical research advances within reach
Putting biomedical research advances within reach
Treatments and vaccines are only useful in the hands of the people who need them, and Penn Medicine is working toward better access and equity for biomedical innovations.
In the News
RNZ/Radio New Zealand
Trial results offer hope to Kiwis with ‘incurable’ blood cancer
Carl June of the Perelman School of Medicine praises New Zealand research into a new CAR T-cell cancer treatment for patients with blood cancer.
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NPR
Long COVID brain fog may originate in a surprising place, say scientists
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID’s neurological symptoms, like brain fog, memory loss, and fatigue, may stem from serotonin reduction.
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Time
Long COVID research is in its ‘most hopeful’ phase yet
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that serotonin could be a target for long COVID treatment.
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ScienceAlert
A crucial pattern behind long COVID may have been identified
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues suggests that several current hypotheses for the pathophysiology of long COVID are linked by a single pathway that is connected by serotonin reduction.
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WebMD
Study of serotonin levels offers hope for long COVID treatment
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID is associated with lower levels of circulating serotonin, which could be relevant for its neurological, cognitive, and memory symptoms.
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WGN-TV
New research links symptoms of long COVID to serotonin levels—and more
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues shows that long COVID can deplete peripheral serotonin levels, offering a baseline for treatment with serotonin supplementation.
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