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Shujie Yang harnesses sound to build the next generation of microrobotic medicine
Shujie Yang

Shujie Yang is at the frontier of single-cell acoustic manipulation, an emerging field that blends physics, mechanobiology, and medicine.

(Image: Courtesy of Penn Engineering)

Shujie Yang harnesses sound to build the next generation of microrobotic medicine

Yang’s lab at Penn Engineering uses precisely-controlled ultrasound waves to develop microscale tools that can manipulate cells, viruses, and soft materials without physical contact.

Melissa Pappas

2 min. read

20 breakthroughs of 2025
Masoud Akbarzadeh holding up one of the fabricated materials.

The Polyhedral Structures Laboratory is housed at the Pennovation Center and brings together designers, engineers, and computer scientists to reimagine the built world. Using graphic statics, a method where forces are mapped as lines, they design forms that balance compression and tension. These result in structures that use far fewer materials while remaining strong and efficient.

(Image: Eric Sucar)

20 breakthroughs of 2025

From ancient tombs and tiny robots to personalized gene editing and AI weather models, Penn’s 2025 research portfolio showed how curiosity—paired with collaboration—moves knowledge into impact and stretches across disciplines and continents.

5 min. read

Startup recognized for milestones in cancer care
Marco Ruella in the Ruella Lab, collaborating with two lab technicians. Ruella is wearing a white lab coat and holding up a chemical sample. Two of his colleagues are observing the sample.

Marco Ruella, associate professor of medicine at PSOM and hematologist-oncologist at Penn Medicine, collaborates with his colleagues in the Ruella Lab.

nocred

Startup recognized for milestones in cancer care

During the Penn Center for Innovation’s 10th annual Celebration of Innovation, viTToria Biotherapeutics was presented with the Startup of the Year Award for its remarkable progress in the development of promising treatment of T-cell lymphoma.

4 min. read

Early immune clues could help detect and prevent type 1 diabetes
A teen takes a blood sugar reading with an app on their phone.

Image: Halfpoint Images via Getty Images

Early immune clues could help detect and prevent type 1 diabetes

Researchers from Penn Medicine have uncovered new clues in pancreas lymph nodes and the spleen that may stop the disease before insulin is lost forever.

Matt Toal

2 min. read

Florencia Polite: Healer, educator, advocate
Florencia Polite.

Florencia Polite, Penn Medicine’s chief of Academic Specialists in Obstetrics and Gynecology and vice chair of the department’s clinical operations.

(Image: Courtesy of Penn Medicine News)

Florencia Polite: Healer, educator, advocate

At home and overseas, Florencia Polite is on a mission to help patients and physicians understand how RSV vaccines protect newborns.

From Penn Medicine News

2 min. read

New CAR T strategy targets most common form of heart disease
a close-up view of a coronary artery with cholesterol plaque signifying cardiovascular disease and atherosclerosis

Kateryna Kon/Science Photo Library via Getty Images

New CAR T strategy targets most common form of heart disease

Preclinical research from investigators at Penn Medicine shows that experimental CAR T cells block inflammation in arteries, preventing more than two-thirds of the plaque buildup seen in untreated controls.

2 min. read

Public not highly knowledgeable about measles risks or MMR vaccine safety

Public not highly knowledgeable about measles risks or MMR vaccine safety

A recent health survey by the Annenberg Public Policy Center finds that the public is less informed than it should be of measles-related risks and less certain than it used to be of the value of vaccination.

From the Annenberg Public Policy Center

2 min. read