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Immunology

Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

A preclinical study from the Perelman School of Medicine and Penn Medicine’s Abramson Cancer Center that combines RAS inhibition and immunotherapy shows promise for future clinical trials in pancreatic cancer treatment strategies.

Meagan Raeke

1 min. read

‘Anti-vaxxers existed before, but never led governments’
Hindustan Times (Delhi)

‘Anti-vaxxers existed before, but never led governments’

In a Q&A, Drew Weissman of the Perelman School of Medicine says that a rise in anti-vaxxers could lead to deaths from preventable diseases like measles and polio, reversing decades of progress.

Why do women live longer than men?
The New York Times

Why do women live longer than men?

Montserrat Anguera of the School of Veterinary Medicine says that epigenetic factors like climate or chronic stress may also play a role in life span, widening or shrinking the disparities between men and women.

Pursuing vaccines to stop celiac disease
A researcher holding a vaccine vial in a lab next to a microscope.

Image: iStock/nuttapong punna

Pursuing vaccines to stop celiac disease

Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.

Alex Gardner

No evidence that CAR T cell therapy causes secondary cancers
Person in gloves holding a medical bag of liquids.

Image: Courtesy of Penn Medicine

No evidence that CAR T cell therapy causes secondary cancers

In a new study, researchers at Penn Medicine looked for—and did not find—examples where the process of generating CAR T cells caused malignancy.

Kelsey Geesler

The compassionate team behind CAR T cancer breakthroughs
From left, research coordinator Nicolas Sarmiento, project manager Reenie Martins, research coordinator Lee Dengel, and trial sample coordinator Rutendo Manyeka in a hospital.

(From left) Research coordinator Nicolas Sarmiento, project manager Reenie Martins, research coordinator Lee Dengel, and trial sample coordinator Rutendo Manyeka document and prepare paperwork required for T-cell infusion.

(Image: Courtesy of Penn Medicine News)

The compassionate team behind CAR T cancer breakthroughs

The clinical trial support staff at Penn Medicine and the Abramson Cancer Center have helped execute the team science that brings research discoveries from the lab bench to the bedside.

From Penn Medicine News

Keto diet supplement could boost a cancer treatment's effectiveness
HealthDay

Keto diet supplement could boost a cancer treatment's effectiveness

A study by Perelman School of Medicine student Puneeth Guruprasad and postdoc Shan Liu suggests that a component of the keto diet could boost CAR T cell therapy to help treat cancer.