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Bubonic plague left lingering scars on the human genome
Nature

Bubonic plague left lingering scars on the human genome

Ziyue Gao of the Perelman School of Medicine comments on the innovative promise of the University of Chicago’s work uncovering the Black Death’s effect on human genetics.

NIH-funded canine immunotherapy data center charts a path toward transformative therapies
happy looking golden retriever in a clinic's kennel area

Researchers have learned much from treating dogs like Fantine, a golden retriever owned by Penn Vet supporter Richard Lichter, with immunotherapies for cancer, in part because tumors in dogs can closely resemble those in humans. With new support from the National Institutes of Health, a Penn-led team is ensuring such lessons can effectively translate into new therapeutic approaches. (Image: John Donges/Penn Vet)

NIH-funded canine immunotherapy data center charts a path toward transformative therapies

With support recently granted for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new insights in cancer care for people as well as pets.

Katherine Unger Baillie

$50M gift to accelerate Colton Center for Autoimmunity at Penn Medicine
Eight people standing in front of a sign that reads The Colton Center for Autoimmunity, including E. John Wherry, Liz Magill, Larry Jameson, and Kevin Mahoney.

Jonathan Epstein, Penn Medicine’s chief scientific officer; Ezekiel Emanuel, vice provost for global initiatives; Dean J. Larry Jameson; Penn President Liz Magill; Judy and Stewart Colton; E. John Wherry, chair of Systems Pharmacology and Translational Therapeutics; and University of Pennsylvania Health System CEO Kevin Mahoney.

$50M gift to accelerate Colton Center for Autoimmunity at Penn Medicine

The center for autoimmune research brings together star faculty, powering the next generation of autoimmune disease advances.
$50 million gift to University of Pennsylvania for autoimmune disease research
Forbes

$50 million gift to University of Pennsylvania for autoimmune disease research

A $50 million gift from Wharton School alumni Judy and Stewart Colton will further develop the work of the Colton Center for Autoimmunity at the Perelman School of Medicine, with a statement from President Liz Magill.

$50 million gift to Penn is aimed at new treatments for autoimmune disease
Philadelphia Inquirer

$50 million gift to Penn is aimed at new treatments for autoimmune disease

E. John Wherry of the Perelman School of Medicine hopes to find better answers for autoimmune conditions as director of the Colton Center for Autoimmunity, established and now accelerated by alumni Judy and Stewart Colton.

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
Fluorescent microscopic image of three T cells surrounding a cancer cell

Tcells surround a cancer cell to finish it off, but such interactions do not always end with the T cells victorious. Researchers from Penn detail how cancer cells can prompt T cells to ingest bits of cancer cell membrane, a process known as trogocytosis. The cancer may evade immune detection as a result. (Image: Alex Ritter, Jennifer Lippincott Schwartz and Gillian Griffiths, National Institutes of Health)

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response

Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.

Katherine Unger Baillie