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Reimagined Penn Medicine facility set to usher in a bold new era of Immune Health discovery
Penn President J. Larry Jameson, Kevin Mahoney and two others cutting a Penn Medicine ribbon at a Ribbon Cutting ceremony.

(From left) Kevin B. Mahoney, chief executive officer of the University of Pennsylvania Health System; Penn President J. Larry Jameson; Jonathan A. Epstein, dean of the Perelman School of Medicine (PSOM); and E. Michael Ostap, senior vice dean and chief scientific officer at PSOM, at the ribbon cutting at 3600 Civic Center Boulevard.

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Reimagined Penn Medicine facility set to usher in a bold new era of Immune Health discovery

3600 Civic Center Boulevard will bring together key researchers and technologies in Immune Health, the Colton Center for Autoimmunity, and infectious diseases to drive breakthrough science.

Eric Horvath

2 min. read

2026 Elaine Redding Brinster Prize honors breakthrough in immune system research

2026 Elaine Redding Brinster Prize honors breakthrough in immune system research

The Institute for Regenerative Medicine at Penn has awarded the Elaine Redding Brinster Prize in Science or Medicine to Zhijian ‘James’ Chen, a biochemist at UT Southwestern Medical Center in Dallas, for his discovery of the DNA-sensing enzyme cyclic GMP-AMP synthase (cGas) and its role in immune and inflammatory response.

How discoveries become cures
Two doctors in white lab coats in a lab.

Image: Margo Reed

How discoveries become cures

Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures.

3 min. read

Improving T-cell responses to vaccines
Person in mask holding vaccine vial.

Image: franckreporter via Getty Images

Improving T-cell responses to vaccines

Penn Vet and Penn Medicine researchers have modified mRNA vaccines to include the cytokine IL-12 and improve T-cell responses which could improve the body’s ability to fight infections.

3 min. read

Enhanced CAR T cell therapy offers new strategy for lymphoma
3-D rendering of chimeric antigen receptor T (CAR-T) cell therapy, a treatment for a variety of cancers

Image: iStock/Naeblys

Enhanced CAR T cell therapy offers new strategy for lymphoma

A new study from Penn Medicine marks a significant development in the ongoing evolution of CAR T cell therapy, as a novel cytokine-enhanced CAR T that has been tested in patients with blood cancer shows robust response rates.

2 min. read