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Internal Medicine
A New York Times medical mystery and a determined sister saved this patient’s life
A patient in New York with an acute case of bronchitis was in respiratory distress. When family members read a similar account in the New York Times, they tracked down the specialist cited in the article—Maxim Itkin at the Perelman School of Medicine.
Hepatitis C-infected kidneys get a green light for further transplant research
Results from a multicenter study point to expanding the donor kidney supply, and alleviating long transplant wait times, with hep-C infected organs, then treating the disease post-transplant.
Gender parity in heart failure research calls for more women authors and patients
An analysis led by Penn Medicine identifies gender disparities in authorship of heart failure guideline citations and clinical trials.
The perfect balancing act of inflammation rests on a single molecule
A new Penn study reveals a molecular mechanism that helps the body mount balanced responses to deadly infections.
How our body’s internal clocks communicate may impact our overall health
Most cells contain molecular clocks, but the requirement of peripheral clocks for rhythmicity, and their effects on physiology, are not well understood. Now, a new study reveal the roles of the hepatocyte clock in cell communication and metabolism.
The gut shields the liver from fructose-induced damage
A new study shows how excessive consumption of fructose, whether via food or beverage, overwhelms gut defenses and results in the development of fatty liver.
To heal meniscus injuries, researchers go to the heart of a cell
Using an enzyme inhibitor in meniscus cells, a Penn team is able to soften the cells’ nucleus and promote access to previously impassible tissue.
Researchers identify novel genetic variants linked to Type 2 diabetes
Largest-ever study of its kind finds variants that may predispose some people to develop the disease and related conditions like coronary heart disease and chronic kidney disease.
Stimulating immune cleanup crew offers affordable possibility for treating rare genetic disorder
Compounds that mimicked the process known as efferocytosis alleviated signs of leukocyte adhesion deficiency type-1 in an animal model, according to work led by the School of Dental Medicine’s George Hajishengallis
Researchers discover a key mechanism of cytokine storm in Castleman Disease
The discovery by Penn researchers may be applicable to COVID-19 patients, as some experience the same hyper-response of the immune system.
In the News
Potential mpox exposure at school in Port Richmond causes parents to worry: What to know about the virus
Michael Cirigliano of the Perelman School of Medicine says that monkeypox spreads mostly through skin-to-skin contact, though the risk of exposure in normal settings is low.
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Marc Satalof donated 35 gallons of blood in more than 50 years. At 76, the Montco retiree just rolled up his sleeve for the last time
A longtime Philadelphia schoolteacher has completed his final donation of blood at Penn’s Perelman Center for Advanced Medicine, with remarks from Kristin G. Christensen and Donald Siegel of the Perelman School of Medicine.
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Why is my dog sneezing a lot? What’s normal and when to worry
Paolo Silvestrini of the School of Veterinary Medicine says that the most frequent reasons for abrupt, sudden canine sneezing may involve a foreign body or allergic reactions to environmental allergens.
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1 in 4 inmate deaths happens in the same federal prison. Why?
David Vaughn of the Perelman School of Medicine says a delay in diagnosis of testicular cancer of more than six months is an independent predictor of a lower chance of survival.
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Millions of people enter later life carrying an extra 10 to 15 pounds. Should they lose the weight?
Mitchell Lazar of the Perelman School of Medicine says distribution of fat plays a major role in determining how deleterious added weight is.
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Cardiovascular disease: New tool may help predict risk in people with chronic kidney disease
Researchers at the Perelman School of Medicine have developed a new, more accurate risk model for cardiovascular disease in patients with chronic kidney disease.
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