Internal Medicine | Penn Today

graphic of a person with both gum inflammation and arthritis in an elbow, showing the cells involved in the relationship between the two conditions

How one inflammatory disorder exacerbates another

Researchers from the School of Dental Medicine and colleagues from Dresden, Germany demonstrate that an association between conditions such as severe gum disease and arthritis is traceable to the bone marrow.

Young child laying on their back putting their feet on an exercise ball with an adult helping and an X ray on the wall.

A possible key to supporting muscle regeneration in Duchenne muscular dystrophy

New Perelman School of Medicine research found that restoring a single protein in muscles affected by the genetic disorder Duchenne muscular dystrophy improved their ability to heal.

Tray of vials used for hepatitis c screening.

No-click system doubles hepatitis C screening orders

A Penn Medicine study finds that screening rates climbed to 80% for patients whose doctors didn’t need to opt in to order a screening.

Hand of a medical professional underneath a virtual rendering of a pancreas.

‘Mapping’ pancreatic cells at the development of Type 1 diabetes

Penn Medicine researchers examine of the underpinnings of the disease by creating a “map” to chart pancreatic islet cells over time.

Side-by-side panels labeled with 1 nanometer scale bar show atomic structure of asbestos

Interaction with lung cells transforms asbestos particles

To better understand what happens once asbestos enters a human body, researchers in the School of Arts & Sciences took a nanoscale look at the mineral.

In two panels labeled "control skin" and "AD skin" stained cells show how inflammation is present in patients with atopic dermatitis

A serendipitous finding lends new insight into how atopic dermatitis develops

Research from the School of Dental Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory reveals a mechanism behind the inflammation that is a feature of the common skin disease.

A structural blueprint of nanoparticles to target acute lung inflammation

Targeting neutrophils, a type of white blood cell that, when overactive, contributes to acute lung inflammation, is a potential new route to diagnose and treat acute respiratory distress syndrome.

Doctor wearing a mask checks the blood pressure of a patient also wearing a mask.

Heart disease-protective diabetes drug is not used equitably

The medication GLP-1 RA treats diabetes and is linked to positive outcomes for heart disease patients, yet a Penn Medicine study has found inequities in its use along racial, ethnic, and economic lines

Common cardiac device implants and persistent opioid use overlap

A new study from Penn Medicine shows that about 12% of patients who receive implantable cardiac devices will continue taking pain medication in the months afterward.

Common gene variants linked to sepsis and COVID-19 severity in African Americans

Two genetic risk variants that are carried by nearly 40% of Black individuals may exacerbate the severity of both sepsis and COVID-19. A Penn Medicine study identifies two potential pathways to reduce the health disparities driven by these gene mutations.

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