11/15
Internal Medicine
A New York Times medical mystery and a determined sister saved this patient’s life
A New York Times medical mystery and a determined sister saved this patient’s life
A patient in New York with an acute case of bronchitis was in respiratory distress. When family members read a similar account in the New York Times, they tracked down the specialist cited in the article—Maxim Itkin at the Perelman School of Medicine.
Hepatitis C-infected kidneys get a green light for further transplant research
Hepatitis C-infected kidneys get a green light for further transplant research
Results from a multicenter study point to expanding the donor kidney supply, and alleviating long transplant wait times, with hep-C infected organs, then treating the disease post-transplant.
Gender parity in heart failure research calls for more women authors and patients
Gender parity in heart failure research calls for more women authors and patients
An analysis led by Penn Medicine identifies gender disparities in authorship of heart failure guideline citations and clinical trials.
The perfect balancing act of inflammation rests on a single molecule
The perfect balancing act of inflammation rests on a single molecule
A new Penn study reveals a molecular mechanism that helps the body mount balanced responses to deadly infections.
How our body’s internal clocks communicate may impact our overall health
How our body’s internal clocks communicate may impact our overall health
Most cells contain molecular clocks, but the requirement of peripheral clocks for rhythmicity, and their effects on physiology, are not well understood. Now, a new study reveal the roles of the hepatocyte clock in cell communication and metabolism.
The gut shields the liver from fructose-induced damage
The gut shields the liver from fructose-induced damage
A new study shows how excessive consumption of fructose, whether via food or beverage, overwhelms gut defenses and results in the development of fatty liver.
To heal meniscus injuries, researchers go to the heart of a cell
To heal meniscus injuries, researchers go to the heart of a cell
Using an enzyme inhibitor in meniscus cells, a Penn team is able to soften the cells’ nucleus and promote access to previously impassible tissue.
Researchers identify novel genetic variants linked to Type 2 diabetes
Researchers identify novel genetic variants linked to Type 2 diabetes
Largest-ever study of its kind finds variants that may predispose some people to develop the disease and related conditions like coronary heart disease and chronic kidney disease.
Stimulating immune cleanup crew offers affordable possibility for treating rare genetic disorder
Stimulating immune cleanup crew offers affordable possibility for treating rare genetic disorder
Compounds that mimicked the process known as efferocytosis alleviated signs of leukocyte adhesion deficiency type-1 in an animal model, according to work led by the School of Dental Medicine’s George Hajishengallis
Researchers discover a key mechanism of cytokine storm in Castleman Disease
Researchers discover a key mechanism of cytokine storm in Castleman Disease
The discovery by Penn researchers may be applicable to COVID-19 patients, as some experience the same hyper-response of the immune system.
In the News
Fox 29 (Philadelphia)
Shoppers react after 10 million pounds of meat recalled due to listeria contamination
Michael Cirigliano of the Perelman School of Medicine says that people who ate recalled chicken within the last day should be watched to ensure they aren’t developing fever, diarrhea, or nausea.
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KFF Health News
Patients are relying on Lyft, Uber to travel far distances to medical care
According to Krisda Chaiyachati of the Perelman School of Medicine, some insurance companies and cancer treatment centers pay for ride-hailing services to reduce missed medical appointments.
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Philadelphia Inquirer
Fox 29 anchor Mike Jerrick diagnosed with prostate cancer, recovering from surgery
Michael Cirigliano of the Perelman School of Medicine made the initial diagnosis of prostate cancer for veteran newscaster Mike Jerrick.
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Fox 29 (Philadelphia)
Philadelphia heat: Tips to avoid heat-related illness as dangerous heat lingers
Michael Cirigliano of the Perelman School of Medicine says that heat stroke, which can be fatal, starts as heat exhaustion then leads to more symptoms as the temperature rises.
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Time
What competitive eating does to the body
David Metz of the Perelman School of Medicine explains some of the effects of speed-eating.
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Stat
As a primary care physician, here’s how I hope to partner with AI
In an opinion essay, Jeffrey Millstein of the Perelman School of Medicine says that patients and clinicians should be active participants when incorporating AI into primary care.
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