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Internal Medicine

Interaction with lung cells transforms asbestos particles
Side-by-side panels labeled with 1 nanometer scale bar show atomic structure of asbestos

Interaction with lung cells transforms asbestos particles

To better understand what happens once asbestos enters a human body, researchers in the School of Arts & Sciences took a nanoscale look at the mineral.

Katherine Unger Baillie

A serendipitous finding lends new insight into how atopic dermatitis develops
In two panels labeled "control skin" and "AD skin" stained cells show how inflammation is present in patients with atopic dermatitis

New findings in atopic dermatitis reveal an inflammatory cascade unfolding early in disease development, according to researchers from the School of Dental Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. (Image: Courtesy of Kang Ko)

A serendipitous finding lends new insight into how atopic dermatitis develops

Research from the School of Dental Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory reveals a mechanism behind the inflammation that is a feature of the common skin disease.

Katherine Unger Baillie

A structural blueprint of nanoparticles to target acute lung inflammation
X-ray of lungs illuminated in red.

A structural blueprint of nanoparticles to target acute lung inflammation

Targeting neutrophils, a type of white blood cell that, when overactive, contributes to acute lung inflammation, is a potential new route to diagnose and treat acute respiratory distress syndrome.

From Penn Medicine News

Heart disease-protective diabetes drug is not used equitably
Doctor wearing a mask checks the blood pressure of a patient also wearing a mask.

Heart disease-protective diabetes drug is not used equitably

The medication GLP-1 RA treats diabetes and is linked to positive outcomes for heart disease patients, yet a Penn Medicine study has found inequities in its use along racial, ethnic, and economic lines

From Penn Medicine News

Common cardiac device implants and persistent opioid use overlap
White pills in a pile.

Common cardiac device implants and persistent opioid use overlap

A new study from Penn Medicine shows that about 12% of patients who receive implantable cardiac devices will continue taking pain medication in the months afterward.

Brandon Lausch

Common gene variants linked to sepsis and COVID-19 severity in African Americans
Microscopic rendering of sepsis cells.

Common gene variants linked to sepsis and COVID-19 severity in African Americans

Two genetic risk variants that are carried by nearly 40% of Black individuals may exacerbate the severity of both sepsis and COVID-19. A Penn Medicine study identifies two potential pathways to reduce the health disparities driven by these gene mutations.

Lauren Ingeno

Novel gene therapy for hemophilia A
graphic of red blood cells in a vein

Novel gene therapy for hemophilia A

The multicenter study, led by researchers at the Perelman School of Medicine and Children’s Hospital of Philadelphia, showed improved and sustained production of a needed clotting factor and reduced bleeding events.

Katherine Unger Baillie

A self-help guide to treating IBD
Image of a book cover, with a purple ribbon placed on top of a hand. The title reads," Coping with Crohn's and colitis: A patient and clinician's guide to CBT for IBD," by "Melissa G. Hunt, Foreword by Aaron T. Beck" next to a photo of a person standing up, wearing a black blazer and a black and gold dress.

A self-help guide to treating IBD

In her new book, clinical psychologist Melissa Hunt offers a cognitive behavioral therapy approach to helping people with Crohn’s disease and ulcerative colitis improve their quality of life.

Michele W. Berger

Can food assistance influence diabetes trends in the U.S.?
Senior citizen wearing a mask holding a shopping basket in a grocery store aisle.

nocred

Can food assistance influence diabetes trends in the U.S.?

In a new study, researchers investigate the relationship between the prevalence of diabetes at the county-level and state SNAP policies, with findings that suggest SNAP could play a key role in the health of communities.  

From Penn LDI

New study illuminates the biology of common heart disorder
Gold-colored human heart model

New study illuminates the biology of common heart disorder

Dilated cardiomyopathy, an often fatal heart disorder, due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin.

Brandon Lausch