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Internal Medicine

Novel gene therapy for hemophilia A
graphic of red blood cells in a vein

Novel gene therapy for hemophilia A

The multicenter study, led by researchers at the Perelman School of Medicine and Children’s Hospital of Philadelphia, showed improved and sustained production of a needed clotting factor and reduced bleeding events.

Katherine Unger Baillie

A self-help guide to treating IBD
Image of a book cover, with a purple ribbon placed on top of a hand. The title reads," Coping with Crohn's and colitis: A patient and clinician's guide to CBT for IBD," by "Melissa G. Hunt, Foreword by Aaron T. Beck" next to a photo of a person standing up, wearing a black blazer and a black and gold dress.

A self-help guide to treating IBD

In her new book, clinical psychologist Melissa Hunt offers a cognitive behavioral therapy approach to helping people with Crohn’s disease and ulcerative colitis improve their quality of life.

Michele W. Berger

Can food assistance influence diabetes trends in the U.S.?
Senior citizen wearing a mask holding a shopping basket in a grocery store aisle.

nocred

Can food assistance influence diabetes trends in the U.S.?

In a new study, researchers investigate the relationship between the prevalence of diabetes at the county-level and state SNAP policies, with findings that suggest SNAP could play a key role in the health of communities.  

From Penn LDI

New study illuminates the biology of common heart disorder
Gold-colored human heart model

New study illuminates the biology of common heart disorder

Dilated cardiomyopathy, an often fatal heart disorder, due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin.

Brandon Lausch

Geographic disparities in lower extremity amputation rates
Person in hospital bed leaning forward while a doctor checks their back with a stethoscope.

Geographic disparities in lower extremity amputation rates

A new study published in the Journal of the American Heart Association shows that peripheral artery disease affects Black people and those of low socioeconomic status, and the U.S. health system is missing opportunities to slow or stop the progression.

From Penn LDI

Imaging technology maps cells tied to inflammatory bowel disease
Microscopic multicolor image of a colon.

Multicolor image of a colon from a patient with ulcerative colitis stained by imaging mass cytometry. (Image: Courtesy of Ayano Kondo from the Kaestner Lab)

Imaging technology maps cells tied to inflammatory bowel disease

“Imaging mass cytometry” shows how cells tied to inflammatory bowel disease affect intestinal tissue, generating new theories for the progression of Crohn’s disease and ulcerative colitis.

From Penn Medicine News