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Internal Medicine

Common cardiac device implants and persistent opioid use overlap
White pills in a pile.

Common cardiac device implants and persistent opioid use overlap

A new study from Penn Medicine shows that about 12% of patients who receive implantable cardiac devices will continue taking pain medication in the months afterward.

Brandon Lausch

Common gene variants linked to sepsis and COVID-19 severity in African Americans
Microscopic rendering of sepsis cells.

Common gene variants linked to sepsis and COVID-19 severity in African Americans

Two genetic risk variants that are carried by nearly 40% of Black individuals may exacerbate the severity of both sepsis and COVID-19. A Penn Medicine study identifies two potential pathways to reduce the health disparities driven by these gene mutations.

Lauren Ingeno

Novel gene therapy for hemophilia A
graphic of red blood cells in a vein

Novel gene therapy for hemophilia A

The multicenter study, led by researchers at the Perelman School of Medicine and Children’s Hospital of Philadelphia, showed improved and sustained production of a needed clotting factor and reduced bleeding events.

Katherine Unger Baillie

A self-help guide to treating IBD
Image of a book cover, with a purple ribbon placed on top of a hand. The title reads," Coping with Crohn's and colitis: A patient and clinician's guide to CBT for IBD," by "Melissa G. Hunt, Foreword by Aaron T. Beck" next to a photo of a person standing up, wearing a black blazer and a black and gold dress.

A self-help guide to treating IBD

In her new book, clinical psychologist Melissa Hunt offers a cognitive behavioral therapy approach to helping people with Crohn’s disease and ulcerative colitis improve their quality of life.

Michele W. Berger

Can food assistance influence diabetes trends in the U.S.?
Senior citizen wearing a mask holding a shopping basket in a grocery store aisle.

nocred

Can food assistance influence diabetes trends in the U.S.?

In a new study, researchers investigate the relationship between the prevalence of diabetes at the county-level and state SNAP policies, with findings that suggest SNAP could play a key role in the health of communities.  

From Penn LDI

New study illuminates the biology of common heart disorder
Gold-colored human heart model

New study illuminates the biology of common heart disorder

Dilated cardiomyopathy, an often fatal heart disorder, due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin.

Brandon Lausch

Geographic disparities in lower extremity amputation rates
Person in hospital bed leaning forward while a doctor checks their back with a stethoscope.

Geographic disparities in lower extremity amputation rates

A new study published in the Journal of the American Heart Association shows that peripheral artery disease affects Black people and those of low socioeconomic status, and the U.S. health system is missing opportunities to slow or stop the progression.

From Penn LDI