Internal Medicine

Doctor wearing a mask checks the blood pressure of a patient also wearing a mask.

Heart disease-protective diabetes drug is not used equitably

The medication GLP-1 RA treats diabetes and is linked to positive outcomes for heart disease patients, yet a Penn Medicine study has found inequities in its use along racial, ethnic, and economic lines

Common cardiac device implants and persistent opioid use overlap

A new study from Penn Medicine shows that about 12% of patients who receive implantable cardiac devices will continue taking pain medication in the months afterward.

Common gene variants linked to sepsis and COVID-19 severity in African Americans

Two genetic risk variants that are carried by nearly 40% of Black individuals may exacerbate the severity of both sepsis and COVID-19. A Penn Medicine study identifies two potential pathways to reduce the health disparities driven by these gene mutations.

Novel gene therapy for hemophilia A

The multicenter study, led by researchers at the Perelman School of Medicine and Children’s Hospital of Philadelphia, showed improved and sustained production of a needed clotting factor and reduced bleeding events.

Image of a book cover, with a purple ribbon placed on top of a hand. The title reads," Coping with Crohn's and colitis: A patient and clinician's guide to CBT for IBD," by "Melissa G. Hunt, Foreword by Aaron T. Beck" next to a photo of a person standing up, wearing a black blazer and a black and gold dress.

A self-help guide to treating IBD

In her new book, clinical psychologist Melissa Hunt offers a cognitive behavioral therapy approach to helping people with Crohn’s disease and ulcerative colitis improve their quality of life.

Senior citizen wearing a mask holding a shopping basket in a grocery store aisle.

Can food assistance influence diabetes trends in the U.S.?

In a new study, researchers investigate the relationship between the prevalence of diabetes at the county-level and state SNAP policies, with findings that suggest SNAP could play a key role in the health of communities.

New study illuminates the biology of common heart disorder

Dilated cardiomyopathy, an often fatal heart disorder, due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin.

A ‘dented’ internal clock informs shift workers’ weight gain and diabetes

Weight gain and high blood sugar caused by a damaged internal clock was corrected by Penn researchers, who changed the length of the day in tests.

Red blood cells play much larger role in immune system via DNA-binding

Penn Medicine researchers have uncovered mechanism of how red blood cells detect and bind DNA, opening a new area of research for treatment of inflammatory diseases.

Doctor wearing a white coat and latex gloves holds up an oxygen mask.

General anesthesia just as safe as spinal anesthesia after broken hip surgery

Challenging common beliefs, Penn research shows patterns of recovery to be similar for patients who received spinal anesthesia and those who got general anesthesia.

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