Internal Medicine | Penn Today

Cross section of a hair follicle surrounded by cells.

Cytokine treatment promotes weight loss by ‘sweating’ fat

A seemingly unremarkable observation—greasy hair—showed Penn researchers how the immune system could be targeted to reverse obesity.

Sharlene M. Day looking in a microscope in a lab wearing a lab coat and latex gloves.

Getting to the heart of genetic cardiovascular diseases

Day, a physician-scientist and cardiologist works to unlock the mysteries of genetic heart disease, integrating translational and clinical science to understand the full spectrum of genetic heart disease evolution and progression.

Lipid panel with check marks with a stethoscope resting on top of the file.

Lipids model how to explore for unexpected diseases

Lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems.

Diagram of lungs comprised of microscopic dots.

Med study illuminates the molecular details of lung development

Researchers at Penn Medicine have produced a detailed molecular atlas of lung development, key for future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

Hand holding a blood pressure gauge measuring the blood pressure of another person whose arm is extended.

Racial and ethnic factors affect access to treatment for heart disease

Researchers uncover a link between racial, ethnic, and socioeconomic factors and whether Black, Latinx, and lower-income patients receive rhythm control strategies for atrial fibrillation.

A close of a neuron with green, red, and blue fluorescent labeling

Parkinson's disease pathology is tied to the activity of cell's 'recycling centers'

Genetic variations associated with both increases and reductions in risk of the neurodegenerative disease alter the action of ion channels within cellular organelles called lysosomes, a new Penn study finds.

Artistic rendering of a cross section of a kidney.

Too many donor kidneys are discarded in U.S. before transplantation

A new study finds kidneys discarded as low-quality in the U.S are similar to kidneys transplanted with acceptable outcomes in France.

Black and white microscopic image of many cells clustered tightly

Gut cells sound the alarm when parasites invade

A chain reaction led by cells lining the intestines tips the immune system off to the presence of the parasite Cryptosporidium, according to a study led by researchers in the School of Veterinary Medicine.

African American person lying on a hospital bed asleep.

Closing the racial disparity gap in survival after in-hospital cardiac arrest

Despite investments to improve the quality of resuscitation efforts, fewer than 25% of all patients that experience cardiac arrests in hospitals survive to discharge, and survival varies significantly across hospitals and by race.

Two people wearing face coverings unload boxes of food for a food bank.

Researchers find link between food insecurity and cardiovascular death risk

Increasing rates of food insecurity in counties across the United States are independently associated with an increase in cardiovascular death rates among adults between the ages of 20 and 64.

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