Internal Medicine | Penn Today

Researchers discover test to predict which patients with rare blood disease will respond to only FDA-approved treatment, and identify alternative therapy

David Fajgenbaum and Sheila Pierson of the Perelman School of Medicine discuss their latest research and findings in the treatment of Castleman disease.

Stacy Haley standing near a vase of flowers holding out an arm.

The best new implants may be a piece of you

Innovative techniques like autologous surgery involves implanting patients with something taken from a different part of their body, which eliminates the risk of infection and erosion of synthetic materials.

Tower Health’s liver and kidney transplant program will move to Penn Medicine

Tower Health announced Wednesday that instead of closing the liver and kidney transplant program it inherited two years ago from the shuttered Hahnemann University Hospital outright, it will let Penn Medicine take it over. Patient screening and pre- and post-transplant care will continue at Reading Hospital in Berks County, but surgeries will move to Penn’s Hospital of the University of Pennsylvania in Philadelphia in mid-December.

Relaxed patient asleep in a hospital bed.

Minimizing disruption, maximizing sleep in the hospital

The Pavilion at the Hospital of the University of Pennsylvania has embraced the challenge of design for minimizing sleep disruption in hospitals.

Cross section of a hair follicle surrounded by cells.

Cytokine treatment promotes weight loss by ‘sweating’ fat

A seemingly unremarkable observation—greasy hair—showed Penn researchers how the immune system could be targeted to reverse obesity.

Sharlene M. Day looking in a microscope in a lab wearing a lab coat and latex gloves.

Getting to the heart of genetic cardiovascular diseases

Day, a physician-scientist and cardiologist works to unlock the mysteries of genetic heart disease, integrating translational and clinical science to understand the full spectrum of genetic heart disease evolution and progression.

Lipid panel with check marks with a stethoscope resting on top of the file.

Lipids model how to explore for unexpected diseases

Lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems.

Diagram of lungs comprised of microscopic dots.

Med study illuminates the molecular details of lung development

Researchers at Penn Medicine have produced a detailed molecular atlas of lung development, key for future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

Hand holding a blood pressure gauge measuring the blood pressure of another person whose arm is extended.

Racial and ethnic factors affect access to treatment for heart disease

Researchers uncover a link between racial, ethnic, and socioeconomic factors and whether Black, Latinx, and lower-income patients receive rhythm control strategies for atrial fibrillation.

A close of a neuron with green, red, and blue fluorescent labeling

Parkinson's disease pathology is tied to the activity of cell's 'recycling centers'

Genetic variations associated with both increases and reductions in risk of the neurodegenerative disease alter the action of ion channels within cellular organelles called lysosomes, a new Penn study finds.

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