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Internal Medicine
Novel model for studying intestinal parasite could advance vaccine development
The intestinal parasite Cryptosporidium causes frequent outbreaks in the U.S., and has been historically difficult to study. A novel model of infection from Penn Vet serves as a new tool to pursue a vaccine.
How to quell a cytokine storm
An international team finds new ways to dampen an overactive immune system, and can influence new drug targets for lupus and other autoimmune disorders.
We’re only as good as our microbiomes are happy
Understanding the microbiome, the collection of bacteria, viruses, and fungi in the gut, is helping to sort out the intricacies of diet, chronobiology, cancer treatment, and more.
Certain strains of bacteria associated with diabetic wounds that do not heal
A new study finds that whether a wound like a diabetic foot ulcer heals or progresses to a worse outcome, including infection or even amputation, may depend on the microbiome within that wound.
App predicts risk of developing hernia following abdominal surgery
A Penn-developed app can predict the likelihood that a patient will develop an incisional hernia following abdominal surgery, utilizing electronic health records to identify the most common risk factors for patients.
A DIY colorectal cancer screening kit
At-home screening kits are found to be effective, with roughly a quarter of patients overdue for screenings mailing the completed kits back within two months.
Hep C-infected organs may be viable option for patients awaiting a heart transplant
Successfully treating the virus post-transplant has the potential for expanding the use of HCV-infected organs, including hearts, to broaden the donor pool for those on a transplant waitlist.
What’s overlooked can be fatal
New research shows that spontaneous coronary artery dissection is not only far more common than was previously thought, but that patients may benefit most from conservative treatment that allows the body to heal on its own.
Immune profiling: A new opportunity for drug development
Immunologists, oncologists, and infectious disease specialists are thinking about the immune system in a new way based on its integral and ubiquitous ties to human health, amassing data on its role in gastroenterology, neurology, cardiovascular disease, and metabolic disease.
To resolve inflammation, location matters
A single protein can both restrain the initiation of inflammation and help to actively resolve it, according to new research led by George Hajishengallis of the School of Dental Medicine. He and his colleague found that the type of cell that secretes the protein determines which activity the protein promotes.
In the News
Potential mpox exposure at school in Port Richmond causes parents to worry: What to know about the virus
Michael Cirigliano of the Perelman School of Medicine says that monkeypox spreads mostly through skin-to-skin contact, though the risk of exposure in normal settings is low.
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Marc Satalof donated 35 gallons of blood in more than 50 years. At 76, the Montco retiree just rolled up his sleeve for the last time
A longtime Philadelphia schoolteacher has completed his final donation of blood at Penn’s Perelman Center for Advanced Medicine, with remarks from Kristin G. Christensen and Donald Siegel of the Perelman School of Medicine.
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Why is my dog sneezing a lot? What’s normal and when to worry
Paolo Silvestrini of the School of Veterinary Medicine says that the most frequent reasons for abrupt, sudden canine sneezing may involve a foreign body or allergic reactions to environmental allergens.
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1 in 4 inmate deaths happens in the same federal prison. Why?
David Vaughn of the Perelman School of Medicine says a delay in diagnosis of testicular cancer of more than six months is an independent predictor of a lower chance of survival.
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Millions of people enter later life carrying an extra 10 to 15 pounds. Should they lose the weight?
Mitchell Lazar of the Perelman School of Medicine says distribution of fat plays a major role in determining how deleterious added weight is.
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Cardiovascular disease: New tool may help predict risk in people with chronic kidney disease
Researchers at the Perelman School of Medicine have developed a new, more accurate risk model for cardiovascular disease in patients with chronic kidney disease.
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