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Innate immune training aggravates inflammatory bone loss
Osteoclasts resorbing bone

Image: Love Employee via Getty Images

Innate immune training aggravates inflammatory bone loss

Researchers from the School of Dental Medicine and international collaborators from Germany have investigated the effects of training the innate immune system in experimental models of chronic inflammatory disease, periodontitis and arthritis.
How disorder toughens materials
Sage Fulco demonstrates the machine the group used to test the materials’ toughness. 

Sage Fulco demonstrates the machine the group used to test the materials’ toughness. 

(Image: Courtesy of Penn Engineering Today)

How disorder toughens materials

A team of Penn engineers tested disordered materials and finds that without changing the material but simply altering the internal geometry, the mechanical metamaterial can increase toughness.

Ian Scheffler

How news coverage distorts America’s leading causes of death
person's hand holding a phone with a news story visible

Image: iStock/oatawa

How news coverage distorts America’s leading causes of death

A new study from the Annenberg School for Communication shows how media coverage of sensational risks underemphasized chronic illnesses.

From Annenberg School for Communication

New mRNA therapy could repair damaged lungs
Rendering of damaged lungs.

Image: iStock/Design Cells

New mRNA therapy could repair damaged lungs

Penn researchers have designed an organ-specific mRNA and lipid nanoparticle therapy which could lead to new targeted treatments for damaged organs.

Alex Gardner

Getting to the root of root canals
Person receiving treatment in a dental clinic.

Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

Getting to the root of root canals

Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.