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Livesaving personalized CRISPR editing therapy
Kiran Musunuru and Rebecca Ahrens-Nicklas holding KJ in the hospital.

Penn Medicine’s Kiran Musunuru and Rebecca Ahrens-Nicklas holding KJ post infusion.

(Image: Courtesy of Children’s Hospital of Philadelphia)

Livesaving personalized CRISPR editing therapy

A landmark study from CHOP and Penn Medicine showcases the power of customized gene editing therapy to treat a patient with a rare metabolic disease

Matt Toal

5 min. read

What behavioral strategies motivate environmental action?
Drawing of people in park.

Image: Irina_Strelnikova via Getty Images

What behavioral strategies motivate environmental action?

A collaborative study from researchers affiliated with the Annenberg School for Communication, Annenberg Public Policy Center, and School of Arts & Sciences tested 17 strategies in an “intervention tournament.”

4 min. read

Promising inhibitor combination for hard-to-treat leukemia subtypes
Andres Blanco in a lab at Penn Vet.

Andrés Blanco is an assistant professor of biomedical science at Penn’s School of Veterinary Medicine.

(Image: John Donges)

Promising inhibitor combination for hard-to-treat leukemia subtypes

Researchers from Penn Vet and other institutions have identified a novel inhibitor combination of molecules that induce terminal differentiation for the treatment of human non-APL subtypes of AML.

From Penn Vet

2 min. read

Collaborating with southern Black grandmothers to reimagine scholarship
Staci L. Jones.

Image: Kyle Cassidy/Annenberg School for Communication

Collaborating with southern Black grandmothers to reimagine scholarship

For an Annenberg School for Communication dissertation, Staci L. Jones and four grandmother co-authors introduce the Kitchen Scholar Framework. Their work embraces knowledge that goes beyond academia.

3 min. read

Generative AI can help doctors diagnose patients—but is it biased?

Generative AI can help doctors diagnose patients—but is it biased?

A new study by Annnenberg School for Communication professor Damon Centola tests if AI tools could help improve medical care without increasing bias. The findings suggest that “AI can meaningfully augment physician decision-making without introducing inequities in clinical decisions,” Centola says.

First new subtype of Castleman disease discovered in 45 years
David Fajgenbaum in his lab.

David Fajgenbaum is an assistant professor of medicine at the Perelman School of Medicine at the University of Pennsylvania and associate director of patient impact in the Penn Orphan Disease Center. He also leads the Castleman Disease Research Program.

(Image: Courtesy of Penn Medicine)

First new subtype of Castleman disease discovered in 45 years

A new study co-authored by Penn Medicine’s David Fajgenbaum expands the spectrum of the rare disorder, which will help diagnose and treat patients caught between existing classification systems.

2 min. read