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Research
Before geoengineering, some fundamental chemistry
Before geoengineering, some fundamental chemistry
Research led by Joseph S. Francisco of the School of Arts & Sciences examines the chemistry of a proposal to curb climate change’s effects—creating a sunshade in the upper atmosphere made of sulfuric acid—and finds that there’s more work to do to successfully pull off such a feat.
From corals to humans, a shared trigger for sperm to get in motion
From corals to humans, a shared trigger for sperm to get in motion
Coral sperm require a specific pH to move, according to research from the School of Arts & Sciences, which identifies a signaling pathway that is shared by organisms including humans. The results inform how corals may fare with climate change.
Novel gene therapy for hemophilia A
Novel gene therapy for hemophilia A
The multicenter study, led by researchers at the Perelman School of Medicine and Children’s Hospital of Philadelphia, showed improved and sustained production of a needed clotting factor and reduced bleeding events.
Practical tools to help you bring your conscience to work
Practical tools to help you bring your conscience to work
A new book by Wharton professor G. Richard Shell serves as a guide to help you stand by your values and create a more ethical workplace.
A new class of CAR T cells targets previously untargetable cancer drivers
A new class of CAR T cells targets previously untargetable cancer drivers
Focusing on neuroblastoma, researchers from the Perelman School of Medicine and Children’s Hospital of Philadelphia have harnessed the immune system to destroy tumors.
Drugs designed for prostate cancer may treat melanoma in men
Drugs designed for prostate cancer may treat melanoma in men
A new Penn study finds that testosterone contributes to sex differences in melanoma via the activation of the zinc transporter ZIP9.
A new model for how the brain perceives unique odors
A new model for how the brain perceives unique odors
Using statistical physics and insights from biology, this research can help inform new hypotheses and experiments towards understanding the olfactory system, a complex and crucial pathway of the brain.
‘Nanozyme’ therapy prevents harmful dental plaque buildup
‘Nanozyme’ therapy prevents harmful dental plaque buildup
An iron-oxide nanoparticle that is FDA-approved to treat anemia acts as an enzyme to activate hydrogen peroxide to suppress the growth of tooth-decay-causing biofilms in the human mouth, according to a study led by the School of Dental Medicine.
Novel gene therapy platform speeds search for ways to cure blindness
Novel gene therapy platform speeds search for ways to cure blindness
A newly developed single-cell RNA sequencing technique enables researchers to quickly identify an optimal vector for delivering therapeutic genetic material to treat vision disorders, and perhaps other genetic conditions.
Eight Penn researchers receive 2021 NIH Director’s Awards
Eight Penn researchers receive 2021 NIH Director’s Awards
The National Institutes of Health grants, totaling more than $8 million, will support seven high-risk, high-reward research projects.
In the News
The Wall Street Journal
The quest for treatments to keep weight off after Ozempic
Researchers at Penn are conducting a co-authored study of the brains, fat and muscle cells, and eating patterns of people trying to maintain new body sizes.
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CNN
There’s still no standard test to detect pancreatic cancer early. Scientists are working to change that
A 2020 study from the Perelman School of Medicine found that a blood test to screen for certain biomarkers associated with pancreatic cancer was 92% accurate in its ability to detect disease.
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Fortune
Hedge funder famous for his ‘black swan’ strategy says there’s ‘something immoral’ about America’s reliance on debt—and future generations ‘will bear the burden for this’
A 2023 study by the Wharton School found that the U.S. has about 20 years left for corrective action to fix the national debt before it hits 200% of GDP.
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Kiplinger
Can money buy you happiness? Yes, it can. However…
Research by Matthew Killingsworth of the Wharton School reveals there is no monetary threshold at which money's capacity to improve well-being diminishes.
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Newsweek
Sugar-coated gold nanoparticles could replace some antibiotics
According to a Penn Medicine study, a new therapy involving laser light and sugar-coated gold nanoparticles can reduce tooth decay and infected wounds without needing antibiotics.
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Associated Press
A new strategy to attack aggressive brain cancer shrank tumors in two early tests
A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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