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Research
Novel gene therapy platform speeds search for ways to cure blindness
A newly developed single-cell RNA sequencing technique enables researchers to quickly identify an optimal vector for delivering therapeutic genetic material to treat vision disorders, and perhaps other genetic conditions.
Eight Penn researchers receive 2021 NIH Director’s Awards
The National Institutes of Health grants, totaling more than $8 million, will support seven high-risk, high-reward research projects.
Improved fluorescent amino acids for cellular imaging
New research describes how to insert synthetic fluorescent amino acids into proteins in living cells, with implications for the study of neurological diseases.
New mathematical tools to study opinion dynamics
Using a class of network structures known as discourse sheaves, researchers describe a new, flexible framework for studying how opinions change over social networks.
A two-pronged approach to keep rheumatoid arthritis in check
A new study led by George Hajishengallis of the School of Dental Medicine shows that the protein DEL-1 could reduce the painful inflammation of RA in an animal model.
Penn Medicine and Wistar awarded $11.7 million melanoma research grant
The Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute will fund three new melanoma research projects over five years.
Engineering CAR T cells to activate a bodily response to solid tumors
A new Penn study shows that CAR T cells expressing RN7SL1, a naturally occurring RNA, can activate the body’s natural immune cells against difficult-to-treat cancers.
2022 Breakthrough Prize in Life Sciences awarded to mRNA pioneers Drew Weissman and Katalin Karikó
Weissman and Karikó are honored for engineering modified RNA technology which enabled rapid development of effective COVID-19 vaccines.
Smart dental implants
Geelsu Hwang of the School of Dental Medicine and colleagues are developing a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing to power a tissue-rejuvenating light.
Versatile ‘chemoproteomic probes’ for activity-based protein profiling
A new study uses organohydrazine probes to map chemical reactivty across the proteome, allowing for a diverse classes of proteins and biological pathways to be studied.
In the News
The more students miss class, the worse teachers feel about their jobs
A study co-authored by Michael Gottfried of the Graduate School of Education finds that teacher satisfaction steadily drops as student absenteeism increases.
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Diversity will suffer with five-day office mandates, research suggests
A 2024 Wharton School study found that changing job openings to remote work at startups increased female applicants by 15% and minority applicants by 33%.
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Superhuman vision lets robots see through walls, smoke with new LiDAR-like eyes
Mingmin Zhao of the School of Engineering and Applied Science and colleagues are using radio signals to allow robots to “see” beyond traditional sensor limits.
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Rising student absenteeism may be hurting teacher job satisfaction
A study by Michael Gottfried and Ph.D. student Colby Woods of the Graduate School of Education finds that student absences are linked to lower teacher job satisfaction, which could exacerbate growing teacher shortages.
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Scientists unveil 16+ distinct nerve cell types behind human touch
A study by Wenqin Lo of the Perelman School of Medicine and colleagues used detailed analyses of the genes used by individual nerve cells to identify 16 distinct types of nerve cells in humans.
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Can honeybees and dogs detect cancer earlier than technology?
Cynthia Otto of the School of Veterinary Medicine and colleagues at the Penn Vet Working Dog Center are training dogs to recognize certain cancer odors.
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