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Penn-Designed ‘Swiss Army Knife’ Molecule Captures RNA From Single Cells

Penn-Designed ‘Swiss Army Knife’ Molecule Captures RNA From Single Cells

A multi-disciplinary team from the University of Pennsylvania has published in Nature Methods a first-of-its-kind way to isolate RNA from live cells in their natural tissue microenvironment without damaging nearby cells. This allows the researchers to analyze how cell-to-cell chemical connections influence individual cell function and overall protein production.  

Karen Kreeger , Evan Lerner

Two Behavioral Interventions Help Cancer Patients Struggling with Sleep Issues, Penn Medicine Study Finds

Two Behavioral Interventions Help Cancer Patients Struggling with Sleep Issues, Penn Medicine Study Finds

Cancer patients who are struggling with sleep troubles, due in part to pain or side effects of treatment,  can count on two behavioral interventions for relief  – cognitive behavioral therapy for insomnia (CBT-I) and mindfulness-based stress reduction (MBSR), Penn Medicine researchers repo

Jessica Mikulski

Penn Medicine Epidemiologists Find Bed Bug Hotspots in Philadelphia, Identify Seasonal Trends

Penn Medicine Epidemiologists Find Bed Bug Hotspots in Philadelphia, Identify Seasonal Trends

A new study from Penn Medicine epidemiologists that looked at four years of bed bug reports to the city of Philadelphia found that infestations have been increasing and were at their highest in August and lowest in February. The findings, published ahead of print on January 8 in the Journal of Medical Entomology, point to two possible peak times to strike and eliminate the bugs.

Steve Graff

Penn Medicine: Red Blood Cells Take on Many-Sided Shape During Clotting

Penn Medicine: Red Blood Cells Take on Many-Sided Shape During Clotting

Red blood cells are the body’s true shape shifters, perhaps the most malleable of all cell types, transforming – among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself. While studying how blood clots contract John W.

Karen Kreeger

Penn Biologists Establish New Method for Studying RNA’s Regulatory ‘Footprint’

Penn Biologists Establish New Method for Studying RNA’s Regulatory ‘Footprint’

Increasingly, biologists have come to realize that RNA is not merely a transitional state between DNA and proteins but plays a major role in determining whether and how genes are turned into a protein product. Gaining a deeper understanding of RNA regulation can help scientists shed light on diseases that arise when this function goes awry.

Katherine Unger Baillie

Disparities Run Deep: Parkinson's Patients Utilization of Deep Brain Stimulation Treatment Reduced within Demographic Groups

Disparities Run Deep: Parkinson's Patients Utilization of Deep Brain Stimulation Treatment Reduced within Demographic Groups

Among Parkinson's disease (PD) patients, female, black, and Asian patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson

Kim Menard

Survival Rates Similar for Gunshot, Stabbing Victims Whether Brought to the Hospital by Police or EMS, Penn Medicine Study Finds

Survival Rates Similar for Gunshot, Stabbing Victims Whether Brought to the Hospital by Police or EMS, Penn Medicine Study Finds

A new study from the Perelman School of Medicine at the University of Pennsylvania has found no significant difference in adjusted overall survival rates between gunshot and stabbing (so-called penetrating trauma injuries) victims in Philadelphia whether they were transported to the emergency department by the police department or the eme

Jessica Mikulski

Leading Health Care Executives Optimistic About Health Care Reform, Penn Survey Shows

Leading Health Care Executives Optimistic About Health Care Reform, Penn Survey Shows

Nearly two-thirds (65 percent) of the nation’s leading health care executives say they believe the health care system will be somewhat or significantly better by 2020 than it is today as a result of national health care reform. Additionally, 93 percent believe that the quality of care provided by their own hospital or health system will improve during that time period.

Katie Delach