Health Sciences

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investi

At the heart of brain diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and Parkinson's disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At present, there is no known way to reverse protein misfolding.

A large-scale human immunodeficiency virus (HIV) intervention/education effort aimed at helping South African men take a proactive role in the prevention of that disease has proven successful, an important development considering that country has the largest number of HIV infections in the world.

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

A multi-disciplinary team from the University of Pennsylvania has published in Nature Methods a first-of-its-kind way to isolate RNA from live cells in their natural tissue microenvironment without damaging nearby cells. This allows the researchers to analyze how cell-to-cell chemical connections influence individual cell function and overall protein production.  

Cancer patients who are struggling with sleep troubles, due in part to pain or side effects of treatment,  can count on two behavioral interventions for relief  – cognitive behavioral therapy for insomnia (CBT-I) and mindfulness-based stress reduction (MBSR), Penn Medicine researchers repo

A new study from Penn Medicine epidemiologists that looked at four years of bed bug reports to the city of Philadelphia found that infestations have been increasing and were at their highest in August and lowest in February. The findings, published ahead of print on January 8 in the Journal of Medical Entomology, point to two possible peak times to strike and eliminate the bugs.

Red blood cells are the body’s true shape shifters, perhaps the most malleable of all cell types, transforming – among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself. While studying how blood clots contract John W.

One of the primary social motivations for scientific research is the ability to make better decisions based on the results.

Increasingly, biologists have come to realize that RNA is not merely a transitional state between DNA and proteins but plays a major role in determining whether and how genes are turned into a protein product. Gaining a deeper understanding of RNA regulation can help scientists shed light on diseases that arise when this function goes awry.