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Evolution Can Select for Evolvability, Penn Biologists Find

Evolution Can Select for Evolvability, Penn Biologists Find

Evolution does not operate with a goal in mind; it does not have foresight. But organisms that have a greater capacity to evolve may fare better in rapidly changing environments. This raises the question: does evolution favor characteristics that increase a species’ ability to evolve?

Katherine Unger Baillie

Sons of Cocaine-Using Fathers May Resist Addiction to Drug, Penn Medicine Study Suggests

Sons of Cocaine-Using Fathers May Resist Addiction to Drug, Penn Medicine Study Suggests

A father’s cocaine use may make his sons less sensitive to the drug and thereby more likely to resist addictive behaviors, suggests new findings from an animal study presented by Penn Medicine researchers at Neuroscience 2013, the annual meeting of the Society for Neuroscience.

Steve Graff

Penn Medicine: Study Shows Moms May Pass Effects of Stress to Offspring Via Vaginal Bacteria and Placenta

Penn Medicine: Study Shows Moms May Pass Effects of Stress to Offspring Via Vaginal Bacteria and Placenta

Pregnant women may transmit the damaging effects of stress to their unborn child by way of the bacteria in their vagina and through the placenta, suggest new findings from two animal studies presented by researchers at the University of Pennsylvania at Neuroscience 2013, the annual meeting of the Society for Neuroscience.

Steve Graff

Penn Medicine: APOL1 Gene Speeds Kidney Disease Progression and Failure in Blacks, Regardless of Diabetes Status

Penn Medicine: APOL1 Gene Speeds Kidney Disease Progression and Failure in Blacks, Regardless of Diabetes Status

A large study co-led by Penn Medicine published this week in the New England Journal of Medicine found that African Americans with the APOL1 gene variant experience faster progression of chronic kidney disease (CKD) and have a significantly increased risk of kidney failure, regardless of their diabetes status.

Steve Graff

A Tale of Two Genes: Penn Team Elucidates Evolution of Bitter Taste Sensitivity

A Tale of Two Genes: Penn Team Elucidates Evolution of Bitter Taste Sensitivity

It’s no coincidence that the expression “to leave a bitter taste in one’s mouth” has a double meaning; people often have strong negative reactions to bitter substances, which, though found in healthful foods like vegetables, can also signify toxicity. For this reason, the ability to sense bitterness likely played an important role in human evolution.

Katherine Unger Baillie

Penn Study Identifies New Trigger for Breast Cancer Metastasis

Penn Study Identifies New Trigger for Breast Cancer Metastasis

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA. But, until recently, no one was able to explain how this characteristic influenced disease progression. 

Katherine Unger Baillie