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Health Sciences
Is treatment forever? Success of gene therapy for inherited blindness depends on timing
Is treatment forever? Success of gene therapy for inherited blindness depends on timing
An FDA-approved gene therapy for Leber congenital amaurosis, an inherited vision disorder with a childhood onset and progressive nature, has improved patients’ sight. But new research underscores the importance of further investigation to halt the progression of the disorder.
Competition works better than support or collaboration to increase daily step counts
Competition works better than support or collaboration to increase daily step counts
A clinical trial using a behaviorally designed gamification program found that adding competition to motivate exercise is a catalyst for real results.
The diet-microbiome connection in inflammatory bowel disease
The diet-microbiome connection in inflammatory bowel disease
Dogs with a Crohn’s-like disease fed a special diet were found to have characteristic changes in their gut microbiomes, paralleling changes seen in children with Crohn’s.
Inferno in the rainforest
Inferno in the rainforest
Satellite images have detected more than 100,000 points of fire in the Amazon this year. Scientists Reto Gieré and Alain Plante illuminate some less obvious impacts of the fires, including health threats and climate impacts.
A molecular ‘atlas’ of animal development
A molecular ‘atlas’ of animal development
Scientists have studied the nematode worm Caenorhabditis elegans for decades, making essential contributions to basic science. In the latest milestone, a team uses cutting-edge technology to individually profile the genes expressed in more than 80,000 cells in a developing C. elegans embryo.
Researcher Virginia M.Y. Lee receives $3 million Breakthrough Prize
Researcher Virginia M.Y. Lee receives $3 million Breakthrough Prize
The Breakthrough Prize award recognizes Lee’s work studying underlying mechanisms of neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, and other dementias.
The U.S. and Canada are seven times more likely to prescribe opioids than Sweden
The U.S. and Canada are seven times more likely to prescribe opioids than Sweden
Within 30 days of discharge, nearly half of all surgical patients in the United States received opioids in excess of 200 morphine milligram equivalents, compared to just 11 percent of the patients in Sweden.
No evidence that testosterone reduces cognitive empathy
No evidence that testosterone reduces cognitive empathy
In the largest study of its kind, researchers found that testosterone administration did not affect cognitive empathy, a measure of the ability to recognize another’s feelings and motivations. The finding calls into question the theory that the symptoms of autism are caused by a hyper-masculinized brain.
A potential new treatment for a deadly form of prostate cancer
A potential new treatment for a deadly form of prostate cancer
Blocking a specific protein sets off a chain reaction that results in the death of prostate cancer cells that have spread and are resistant to standard therapies.
Where ethics, welfare, and sustainability meet swine
Where ethics, welfare, and sustainability meet swine
At New Bolton Center’s model pig farm, free-roaming sows are implanted with RFID chips, nourished by organic feed, and powered by solar energy.
In the News
6ABC.com
Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley
Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.
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Self
The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health
Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.
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NPR
Tuberculosis rates plunge when families living in poverty get a monthly cash payout
Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.
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Time
Scientists are racing to develop a new bird flu vaccine
Drew Weissman and Scott Hensley of the Perelman School of Medicine are testing a vaccine to prevent a strain of H5N1 bird flu in chickens and cattle.
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Newsweek
Cancer breakthrough as ‘speckles’ may reveal best treatment
A paper co-authored by PIK Professor Shelley Berger finds that patterns of “speckles” in the heart of tumor cells could help predict how patients with a common form of kidney cancer will respond to treatment options.
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