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At the Crossroads of Chromosomes: Penn Study Reveals Structure of Cell Division’s Key Molecule

At the Crossroads of Chromosomes: Penn Study Reveals Structure of Cell Division’s Key Molecule

PHILADELPHIA – On average, one hundred billion cells in the human body divide over the course of a day. Most of the time the body gets it right but sometimes, problems in cell replication can lead to abnormalities in chromosomes resulting in many types of disorders, from cancer to Down Syndrome.

Why the Biological Clock? Penn Study Says Aging Reduces Centromere Cohesion, Disrupts Reproduction

Why the Biological Clock? Penn Study Says Aging Reduces Centromere Cohesion, Disrupts Reproduction

PHILADELPHIA –- University of Pennsylvania biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes during reproductive cell division.

Jordan Reese

Using the Structure of the Epidermal Growth Factor Receptor to Fight Cancer

Using the Structure of the Epidermal Growth Factor Receptor to Fight Cancer

PHILADELPHIA - Many types of tumors grow because of over-expression or a mutation of a protein called the epidermal growth factor receptor (EGFR), normally regulated by a hormone-like peptide called the epidermal growth factor (EGF).

Karen Kreeger

Dr. J. Larry Jameson to Lead Penn Medicine

Dr. J. Larry Jameson to Lead Penn Medicine

PHILADELPHIA -- J. Larry Jameson, M.D., Ph.D., has been named the next executive vice president of the University of Pennsylvania for the Health System and dean of Penn’s School of Medicine, effective July 1, 2011.

Lori N. Doyle

Penn Nursing's Julie Sochalski Named to Federal Bureau of Health Professions Post

Penn Nursing's Julie Sochalski Named to Federal Bureau of Health Professions Post

The federal Health and Human Services Administration has announced that Penn professor Julie Sochalski, a well-known expert in the field on healthcare workforce issues and who has directed multiple federal research efforts, has been appointed the Director for the Division of Nursing in th

Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations

Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations

Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of developing breast and ovarian cancer.  A study that will appear in the September 1 issue of The Journal of the American Medical Association (JAMA) reports that women with these inherited mutations who have had a prophylactic mastectomy or salpingo-oophorectomy (removal of

Violence in Inner City Neighborhoods Contributes to Trouble With Asthma

Violence in Inner City Neighborhoods Contributes to Trouble With Asthma

PHILADELPHIA –   Patients with asthma who are exposed to violence in their community are at an increased risk for an asthma-related hospitalization and emergency room visits for asthma or any cause, according to new research from the University of Pennsylvania School of Medicine.

Jessica Mikulski

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study

PHILADELPHIA –- A study comparing a University of Pennsylvania method for evaluating a dog’s susceptibility to hip dysplasia to the traditional American method has shown that 80 percent of dogs judged to be normal by the traditional method are actually at risk for developing osteoarthritis and hip dysplasia, according to the Penn method.

Jacquie Posey