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Penn Medicine: Evidence of Alzheimer's in Patients with Lewy Body Disease Tracks with Course of Dementia

Penn Medicine: Evidence of Alzheimer's in Patients with Lewy Body Disease Tracks with Course of Dementia

Patients who had a diagnosis of Parkinson’s disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels  of Alzheimer’s disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the 

Karen Kreeger

Linking Human Genome Sequences to Health Data Will Change Clinical Medicine, says Penn Expert

Linking Human Genome Sequences to Health Data Will Change Clinical Medicine, says Penn Expert

The value of intersecting the sequencing of individuals’ exomes (all expressed genes) or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record (EHR) information has “myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of

Karen Kreeger

Penn Immunotherapy Pioneer Elected to National Academy of Inventors

Penn Immunotherapy Pioneer Elected to National Academy of Inventors

Yvonne J. Paterson, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has been elected a fellow of the National Academy of Inventors. Fellows are named inventors on U.S.

Karen Kreeger

Penn: Epigenetic Change Ties Mitochondrial Dysfunction to Tumor Progression

Penn: Epigenetic Change Ties Mitochondrial Dysfunction to Tumor Progression

Mitochondria, the mighty energy factories of the cell, often malfunction in cancer, as well as in other conditions such as aging, neurodegenerative disease and heart disease. Whether these changes in mitochondria actually contribute to the spread of cancer, however, has been controversial.

Katherine Unger Baillie

Penn’s quest to battle Alzheimer’s
Penn’s Quest to Battle Alzheimer’s

Penn’s quest to battle Alzheimer’s

John Trojanowski and Virginia Man-Yee Lee of the Perelman School of Medicine have been conducting Alzheimer’s research for more than 30 years, and have made three major discoveries—all of which have become strong foundations for those working on Alzheimer’s disease and related disorders around the world.

Lauren Hertzler