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Health Sciences
One protein’s role in genomic intermingling and T cell development
The findings, from a team led by Golnaz Vahedi of Penn Medicine, could have implications for T-cell based immunotherapies for cancer and other conditions.
Identities in harmony: How Beth Burton integrates the personal with the professional
The doctoral candidate in the Perelman School of Medicine is a scientist studying the genetic causes of Alzheimer’s. She’s also a musician, a queer woman, and a voice for those with genetic disorders.
From 5 to 95: The impact of life experiences on brain health
Structural and social determinants of health (SSDoH) are environmental conditions in which individuals are born, live, and learn that affect health, and evidence suggests that SSDoH can help to explain similar outcomes in Alzheimer’s disease.
Climate change’s impact on cardiovascular mortality
Two new studies from Penn LDI indicate the increasing number of extreme heat waves baking large swaths of the country pose new levels of potentially deadly health threats, particularly for older adults and minority populations in low-income communities.
Helping transgender patients navigate health care
Penn Medicine Center for Health Equity Advancement and Penn’s Program for LGBTQ Health works to address the specific health care needs of gender diverse patients.
Managing mental health amid gun violence
In 2021, Philadelphia saw a record number of 486 homicides by shooting as well 1,846 non-fatal shootings. According to clinical psychologist Leah Blain, exposure to trauma, including to gun violence, increases the risk of negative health outcomes.
Children younger than 5 eligible for COVID-19 vaccines
In a Q&A, Lori Handy of Penn Medicine and CHOP discusses what it means now that this final group can get protection, plus offers recommendations for families with concerns about doing so.
Stress protein in fibroblasts may be a good target for future cancer drugs
A Penn study finds the ATF4 protein is overactive in many types of tumor cells and tumor-supporting fibroblasts to promote tumor survival, and may be a good target for future cancer treatments.
A newly identified stem cell regulator enables lifelong sperm production
Research led by Jeremy Wang of the School of Veterinary Medicine has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.
University of Pennsylvania’s first NFT commemorates mRNA research
Proceeds from the July auction of the non-fungible token—a digital asset—will benefit ongoing research at Penn.
In the News
More yogurt and nuts, less alcohol and snack foods: How GLP-1 medications like Ozempic are influencing people’s food spending habits
Carrie Burns of the Perelman School of Medicine says that weight-loss medications tend to decrease cravings for foods high in sugar and fat.
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Migratory birds mainly responsible for bird flu outbreak, experts tell Pa. lawmakers
Louise Moncla of the School of Veterinary Medicine says that avian flu viruses are being spread far geographically because of wild migratory birds.
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Thirteen subtle changes veterinarians would never ignore in their cats
Kaitlyn Krebs of the School of Veterinary Medicine says that cats can indicate illness through behavioral changes such as hiding or spending time in unusual places.
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Drinking two beers daily ages the brain by 10 years; study reveals surprising findings
A study by Penn researchers found that one to two units of alcohol per day shrunk overall brain volume and gray matter volumes.
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Seven unusual sleep hacks to help you drift off peacefully—we speak to a sleep expert about how to get a good night’s rest
A study from the Perelman School of Medicine found that participants who practiced paradoxical intention experienced significantly reduced sleep anxiety.
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