Health Sciences

Some at-risk patients opted out of comprehensive cancer gene screening when presented with the opportunity to be tested for the presence of genes linked to various cancers, according to a recent study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and the 

At the forefront of a field known as “neurocriminology,” Adrian Raine of the University of Pennsylvania has long studied the interplay between biology and environment when it comes to antisocial and criminal behavior.

Researchers from the University of Pennsylvania and Michigan State University presented new preclinical data this week that evaluates the efficacy of a gene therapy treatment for achromatopsia, a rare inherited retinal disease that involves cone cells. The disease affects humans as well as dogs.

A study in this week’s Science Translational Medicine is a classic example of how seemingly unlikely collaborators can come together to make surprising discoveries.

nly half of women with cystic fibrosis (CF) report using contraception and frequently apt to become pregnant unintentionally, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

The Lariat device, which has been cleared by the U.S. Food and Drug Administration (FDA) for soft tissue approximation (placement of a suture) during surgical procedures, is associated with a significant incidence of death and urgent cardiac surgery during its frequent off-label use to prevent stroke in patients with the irregular heartbeat known as atrial fibrillation.

Gene therapy for Leber congenital amaurosis (LCA), an inherited disorder that causes loss of night- and day-vision starting in childhood, improved patients’ eyesight within weeks of treatment in a clinical trial of 15 children and adults at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania.

Researchers from the Perelman School of Medicine and the Penn Center for AIDS Research (CFAR) have been awarded $7.5 million over five years from the National Institutes of Health to initiate a multi-project HIV study investigating a new gene therapy approach to render immune cells of HIV positive patients resistant to the virus.

By Madeleine Stone  @themadstone        (This is the fifth and last in a series of features introducing the inaugural Penn President’s Engagement Prize winners.)  

The National Institutes of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH), has renewed its funding to the Center of Excellence in Environmental Toxicology (CEET), at the University of Pennsylvania’s Perelman School of Medicine, for the next five years.