Science & Technology

With second FDA approval, CAR-T’s transformative power multiplies

After last year’s approval to treat pediatric lymphoma, the latest indication will expand the number of patients that can be treated with personalized cell therapy almost tenfold.

Earthquakes at the nanoscale

Scientists have gotten better at predicting where earthquakes will occur, but they’re still in the dark about when they will strike and how devastating they will be. Penn researchers hope to tackle this by investigating the laws of friction at the smallest possible scale, the nanoscale.

Wrongful convictions reported for 6 percent of crimes

For capital crimes like rape and murder, wrongful convictions happen in about 3 to 5 percent of cases. Such an estimate had proved elusive for the prison population as a whole—until now, thanks to work from Penn criminologists.

A faster way to make drug microparticles

Penn Engineers have developed a liquid assembly line process that controls flow rates to produce particles of a consistent size at a thousand times the speed.

Veterinary experts work to stay ahead of equine doping

As in human sports, unscrupulous practices occasionally make their way into horse racing. Researchers and veterinarians at the School of Veterinary Medicine are keeping an eye on illicit drug use, evaluating samples, and designing tests to maintain the integrity of the sport and keep the competitors safe.

Innovative vaccine offers canine cancer patients a shot at a longer, happier life

Osteosarcoma is the most common bone cancer to affect dogs. It is a painful and aggressive disease. Affecting more than 10,000 dogs annually, predominantly larger breeds, it kills more than 85 percent within two years.

Research from Penn’s Heath Schmidt revealed that drugs already approved by the FDA to treat diabetes and obesity may reduce cocaine relapse and help addicted people break the habit

A potential new weapon in the battle against addiction

New research revealed that FDA-approved drugs to treat diabetes and obesity may reduce cocaine relapse and help addicts break the habit. Such medications work by targeting receptors for glucagon-like peptide 1, a hormone in the brain.

Penn Electric Racing gears up for this years’ competition with an innovative new design

Penn Electric Racing, a team of about 60 students at the University of Pennsylvania, design and build electric cars to race in the Formula SAE Electric competition each year.

Teens might put their phones down while driving. For a price.

Researchers found that teen drivers are receptive to relinquishing some, but not all, mobile device habits, with the right incentives.

Bacteria boost antifungal drug resistance in severe childhood tooth decay

Some young children experience severe tooth decay that resist normal therapies. New research led by Dongyeop Kim and Hyun (Michel) Koo of the School of Dental Medicine shows how plaque’s protective matrix can shield fungal cells from the drugs intended to kill them.

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