Perelman School of Medicine

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Advancing algorithmic care

Experts from Penn share their perspectives on the role of advanced algorithms and AI in health care and what the future holds for digital health technologies.

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A novel approach to treating opioid use disorder

An FDA-approved drug called exendin-4 decreased voluntary oxycodone taking and drug-seeking behavior during withdrawal in rats without reducing the relief the opioid provided.

Positive results in first-in-U.S. trial of CRISPR-edited immune cells

Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient appears safe and feasible based on early data from the first-ever clinical trial to test the approach in humans in the United States.

To monitor cancer therapy, researchers tag CAR T cells with imaging markers

With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. Now scientists have now discovered a new way to track CAR T cells in the body.

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Bariatric surgery is safe for teens with morbid obesity

A new Penn Medicine study shows the risks of complications and readmissions may be lower than the risks associated with lifelong obesity.

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Blood test can predict prognosis in deadly brain cancer

A Penn study points to clinical utility of liquid biopsy in glioblastoma, allowing doctors the ability to measure the progression of the cancer based on the amount of cell-free DNA in the bloodstream

Basser Center takes aim at BRCA

Twenty-five years after the discovery of genetic mutations that dramatically increase cancer risk, the Penn Medicine’s Basser Center for BRCA is building scientific knowledge alongside public awareness about BRCA-related cancers.

Lifelong no longer: New research on TB infection rarely leads to active disease

A Penn-led study suggested majority will not develop disease even if a test shows positive results, citing that the infecting organism, Mycobacterium tuberculosis, is likely dead, wiped out naturally by people’s immune systems.

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Physicians, social responsibility, and sexual assault survivors

Penn Medicine’s Florencia Greer Polite wants doctors to take a more proactive approach to conversations with their patients about consent and sexual abuse.

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A focus on environmental inequities

A Penn symposium will confront issues of inequitable access to a clean and safe environment and the unequal burden borne by vulnerable communities, particularly low-income and underrepresented minority populations, when it comes to environmental threats.

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