Perelman School of Medicine

Clockwise from top left: Stephan A. Grupp, Beverly L. Davidson, James H. Eberwine, Guo-lin Ming, George Demiris, Charles S. Abrams

Six Penn faculty members elected to National Academy of Medicine

One of the nation’s highest honors in biomedicine, members are elected by their peers for accomplishments and contributions to the advancement of the medical sciences, health care, and public health.

Members of LIFT US UP include (from left) Jordan Harris, Michael Perez, Mariam Olujide, Shannon Shipley, Anitra Persaud, and Cheyenne Williams.

Providing a ‘LIFT’ to first-generation med students

All new students face challenges in the transition to college, but for first-generation, low-income (FGLI) students, it’s a whole new world. Providing a community for these students helps counter feelings of isolation and the “impostor” syndrome that FGLI students may experience.

Engineers solve the paradox of why tissue gets stiffer when compressed

Tissue gets stiffer when it’s compressed. That stiffening response is a long-standing biomedical paradox, as common sense dictates that when you push the ends of a string together, it loosens tension, rather than increasing it. New research explains the mechanical interplay between that fiber network and the cells it contains.

Failure of mitochondrial quality control causes heart disease

A new Penn Medicine study reveals a well-known protein participates in mitophagy; mutations in the genes of that protein suppress mitophagy and cause disease.

Researchers unravel the early makings of an exhausted T cell

Knowing which T cells will lose the battle against cancer earlier could inform treatments and the development of new immunotherapies.

computer rendering of microscopic images of DNA helix on the left, a tumor on the right.

Algorithm personalizes which cancer mutations are best targets for immunotherapy

A new model developed by researchers in the Abramson Cancer Center hand-picks cancer cells to target for more effective, customized cancer vaccines.

In pursuit of a cure, when ideas and options have run out

A new book from Penn Medicine’s David Fajgenbaum chronicles his journey to beat Castleman disease, a rare disorder that he’s lived with for almost a decade.

Mounting brain organoid research reignites ethical debate

Penn neuroscientists call for an ethical framework grounded in scientific principles for transplanting human “mini-brains” into animals as the field evolves.

Jason Freedman in foreground on his wedding day to husband Neil, in background.

Q&A

A Q&A with Penn Medicine’s Jason Freedman for National Coming Out Day

The assistant professor of clinical pediatrics discusses being out at Penn and shares some of his own experiences as a gay man.

How safe and effective are new pulmonary embolism devices?

A scientific statement from the American Heart Association, led by Penn Medicine, identifies the risks and benefits of new interventional devices compared to the use of blood thinners alone.

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