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Penn Medicine’s Carl June receives 2018 Albany Prize
june

Penn Medicine’s Carl June receives 2018 Albany Prize

Carl June, a gene therapy pioneer at the Abramson Cancer Center, will receive the 2018 Albany Medical Center Prize in Medicine and Biomedical Research.

Penn Today Staff

Two students’ paths to White Coat Day
ralph_and_rotem

Ralph St. Luce and Rotem Kimia

Two students’ paths to White Coat Day

Ralph St. Luce & Rotem Kimia, two members of a new class of medical students at the Perelman School of Medicine, discuss what brought them to medicine, in anticipation of the school's annual White Coat Ceremony.

Penn Today Staff

Drugs in development for cancer may also fight brain diseases, including ALS
In cells under duress, stress granules (in magenta) form outside of the nucleus (in blue). TDP-43 protein in green (arrow) that cannot bind to PolyADP ribose (PAR) builds up in large clumps distinct from stress granules. (Image: Leeanne McGurk, University of Pennsylvania; Molecular Cell)

In cells under duress, stress granules (in magenta) form outside of the nucleus (in blue). TDP-43 protein in green (arrow) that cannot bind to PolyADP ribose (PAR) builds up in large clumps distinct from stress granules. (Image: Leeanne McGurk, University of Pennsylvania; Molecular Cell)

Drugs in development for cancer may also fight brain diseases, including ALS

In a study done by researchers at the Perelman School of Medicine and the School of Arts and Sciences, PARP inhibitors, which are used for fighting cancer, can be useful for the treatment and prevention of brain disorders such as ALS.

Karen Kreeger

Cancer cells send out ‘drones’ to battle the immune system from afar
Guo cancer drones

Like drones heading for battle, cancer cells emit vesicles containing immunity-suppressing proteins to tamp down T cell responses at sites throughout the body. (Image: Kelsey Burke)

Cancer cells send out ‘drones’ to battle the immune system from afar

Checkpoint inhibitor therapies have made metastatic melanoma and other cancers a survivable condition, but only for some patients. Researchers uncovered a novel mechanism by which tumors suppress the immune system, raising the possibility that a straightforward blood test could predict which patients could respond to immunotherapy.

Karen Kreeger , Katherine Unger Baillie

Ensuring equality with a framework for workforce inclusion
pediatrician

Ensuring equality with a framework for workforce inclusion

A study published in JAMA Network Open from researchers at the Perelman School of Medicine identifies six factors that measure workforce inequality in delivering health care, as part of Office of Inclusion and Diversity’s equality mission.

Penn Today Staff

Dr. Benoit Dubé appointed Chief Wellness Officer
Dubé, Benoit

Dr. Benoit Dubé appointed Chief Wellness Officer

Provost Wendell Pritchett and Vice Provost for University Life Valarie Swain-Cade McCoullum today announced the appointment of Dr. Benoit Dubé, Associate Professor of Clinical Psychiatry, as the University of Pennsylvania’s first Chief Wellness Officer.
Greening vacant lots reduces depression in city dwellers
Criminologist John MacDonald and emergency medicine physician Eugenia South of the University of Pennsylvania.

In the latest round of research on the effects of greening vacant lots, criminologist John MacDonald and emergency medicine physician Eugenia South found that people living within a quarter mile of greened lots had a 41.5 percent decrease in feelings of depression and a nearly 63 percent decrease in self-reported “poor mental health” compared to those who lived near the lots that received no intervention.

Greening vacant lots reduces depression in city dwellers

People living within a quarter mile of greened lots had a 41.5 percent decrease in feelings of depression and a nearly 63 percent decrease in self-reported “poor mental health,” compared to those who lived near the lots that received no intervention.

Katie Delach , Michele W. Berger

The changing landscape of mosquito- and tick-borne diseases
James Lok, Penn Vet

Parasitology professor James Lok’s studies of the development and basic biology of parasites, particularly the roundworm Strongyloides, have implications for finding new drug candidates. Veterinary schools have traditionally been strongholds of parasitology research, and Penn Vet is no exception. (Image: Eric Sucar)

The changing landscape of mosquito- and tick-borne diseases

Lyme disease, West Nile virus, Zika, chikungunya, and dengue are among the vector-borne infections making headlines. Penn researchers shed light on what’s behind the spread and how to stay safe.

Katherine Unger Baillie