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Brain tumor organoids accurately model patient response to CAR T cell therapy
Microscopic view of a glioblastoma organoid.

A patient-derived glioblastoma organoid treated with dual-target CAR-T cells. T cells (magenta) infiltrate the tumor organoid and kill tumor cells (blue; yellow indicates dying cells).

(Image: Yusha Sun and Xin Wang from the laboratories of Guo-li Ming and Hongjun Song)

Brain tumor organoids accurately model patient response to CAR T cell therapy

Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine.

Kelsey Geesler

2 min. read

Care across cultures: Penn Medicine African Health Clinic
Members of Penn’s African Health Clinic.

From check-ups to managing diabetes, treating common illnesses, and X-raying injured extremities, the care team handles a variety of patients’ needs right from the off-site clinics.

(Image: Courtesy of Penn Medicine News)

Care across cultures: Penn Medicine African Health Clinic

For the last two years, the Perelman School of Medicine has partnered with the African Family Health Organization to offer weekly family-medicine/primary care clinics for recent immigrants from Africa and the Caribbean.

Alex Gardner

A champion for period products in Pennsylvania schools
An adult giving a high school student menstrual pads.

Image: iStock/Valeriy_G

A champion for period products in Pennsylvania schools

Kayla Cook ensures that all middle and high school students in a Lancaster school district have access to dispensing bins, which hold tampons, pads, and liners in every individual women’s or gender-neutral bathroom stall.

From Penn Medicine News

Mark Cuban’s take on prescription drug pricing models
Zeke Emanuel and Mark Cuban in discussion in front of an audience.

Image: Courtesy of Penn LDI

Mark Cuban’s take on prescription drug pricing models

In late November, hundreds of students, researchers, faculty, and staff from Penn’s Wharton School Health Care Management attended a discussion between entrepreneur Mark Cuban and Ezekiel Emanuel.

Hoag Levins

A Q&A with the director of the Penn Center for AIDS Research
Four people in front of National AIDS Memorial Quilt.

Penn researchers affiliated with the Penn Center for AIDS Research (CFAR) attended AIDS Walk Philly in October 2024. Pictured with the National AIDS Memorial Quilt are Deratu Ahmed, a first-year epidemiology doctoral student studying pharmacogenetics related to HIV and tuberculosis in Botswana; Dominique Medaglio, a fourth-year epidemiology doctoral student studying ways to encourage smoking cessation for people with HIV in the United States; CFAR co-director Robert Gross, professor of medicine and epidemiology in the Division of Infectious Diseases at Penn Medicine; and CFAR director Ronald Collman, professor of medicine and microbiology.

(Image: Courtesy of Ronald G. Collman)

  • Q&A

    • A Q&A with the director of the Penn Center for AIDS Research

    Ronald G. Collman talks about the current state of AIDS care, work with the City of Philadelphia, and how the Center is supporting collaborations across campus.
    ‘Deeply Rooted’ community partnerships
    Jovian Patterson looks at some raspberry bushes growing in a community garden.

    Jovian Patterson has used Deeply Rooted community green grants to expand an annual garden class for his West Philadelphia neighbors.

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    ‘Deeply Rooted’ community partnerships

    Deeply Rooted is a community partnership that plants trees, greens vacant lots, and funds grassroots programs. The goal: health justice in action.

    Christina Hernandez Sherwood for Penn Medicine Magazine